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Lanoxin (Digoxin) Dosage Guide in Pakistan

Taking the correct dose of Lanoxin (Digoxin) is absolutely essential for effective treatment and safety. This is a narrow therapeutic index medicine — the dose is individualized and serum level monitoring is required. Never adjust the dose on your own.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated:

Dosage Guide

Quick Answer

Lanoxin (Digoxin) dose is strictly individualized — based on renal function, age, weight, and serum digoxin levels. Typical adult maintenance is 0.125–0.25mg once daily, but your doctor will set the exact dose. Never self-adjust. Narrow therapeutic index — even a small dose increase can cause life-threatening toxicity.

Dose at a Glance

Adult Dose

As prescribed — typically 0.125mg–0.25mg once daily (maintenance); dose individualized based on renal function, age, weight, and serum digoxin level

Once daily, same time

Max: As determined by doctor — serum level target typically 0.5–2.0 ng/mL (0.5–0.9 ng/mL in heart failure)

Child Dose (Specialist paediatric dosing required — not for general self-administration)

Weight-based specialist paediatric dose only — contact your child's cardiologist

As directed by paediatric cardiologist

Missed Dose

If you miss a dose, take it as soon as you remember — if the next dose is close, skip the missed dose. Never take a double dose — a double dose of digoxin can be life-threatening.

Overdose

Digoxin overdose is a medical emergency. Symptoms: severe bradycardia, arrhythmias, xanthopsia (yellow/green vision), nausea/vomiting. Go to the hospital emergency department immediately. Digoxin-specific antibody fragments (Digibind) are used as an antidote.

Lanoxin (Digoxin) Dosage (Kitni leni hai)

CRITICAL: Lanoxin (Digoxin) is a narrow therapeutic index (NTI) medicine. The correct dosage is determined by a qualified doctor — never change the dose on your own. The difference between therapeutic and toxic levels is very small.

Adult Dose (Baalgon ke liye)

  • Maintenance dose: 0.125mg–0.25mg once daily — as prescribed
  • Loading dose: (if given) — usually done in hospital or clinical setting under ECG monitoring
  • Dose is based on renal function, age, body weight, and serum digoxin level
  • Serum digoxin target: 0.5–2.0 ng/mL (generally 0.5–0.9 ng/mL preferred in heart failure)
  • Do not exceed the recommended limit — toxicity is life-threatening
  • If you miss a dose, take it as soon as you remember. If the next dose is close, skip the missed dose. Never take a double dose.

Starting Dose: As determined by doctor — may start low (0.0625mg or 0.125mg) and monitor

Usual Maintenance Dose: 0.125mg–0.25mg once daily — based on individual patient factors

Max Daily Dose: As determined by doctor, guided by serum digoxin levels and clinical response

Elderly Patients (Buzurg Mard aur Khawatin)

  • In elderly patients, the dose is often kept lower (e.g. 0.0625mg or 0.125mg daily)
  • Renal clearance is reduced — risk of accumulation is higher
  • Closer monitoring is required

Renal Impairment (Gurde Ke Marz Mein)

  • Dose reduction is required — degree of reduction depends on GFR/creatinine
  • More frequent serum digoxin level monitoring needed
  • Get dose advice from a specialist (nephrologist/cardiologist)

Child Dose (Bachon ke liye)

Paediatric Digoxin dose is weight-based and is set by a paediatric cardiologist. Do not calculate the dose for children yourself — the toxic dose in children is much lower than in adults.

How to Take (Kaise leni hai)

  • Once daily
  • Always at the same time
  • Morning preferred
  • With or without food — do not take with antacids

Best Time to Take (Kab leni chahiye)

  • Morning — maintain a consistent time
  • Daily at the same time — routine is very important for heart medicines

With Food or Empty Stomach (Khali pait ya khane ke baad)

It can be taken either way. However, absorption is significantly reduced when taken with antacids, cholestyramine, or kaolin-pectin — do not take with these; maintain a 2-hour gap.

Missed Dose (Dose chhoot jaye to kya karein)

If you miss a dose, take it as soon as you remember. If the next dose is close, skip the missed dose. Never take a double dose — a double dose of Digoxin is dangerous.

Overdose (Zyada Dose — Medical Emergency)

Digoxin overdose is a medical emergency.

Signs: severe bradycardia, arrhythmias, xanthopsia (yellow/green visual halos), nausea, vomiting, confusion.

Action: Go to the hospital emergency department immediately. Digoxin-specific antibody fragments (Digibind/DigiFab) are available as an antidote — administered in hospital.

Dose Summary Table

PatientDoseNotes
Adult0.125–0.25mg once daily (typical maintenance)Individualized — renal function + serum level guided
Elderly0.0625–0.125mg once daily (often lower)Lower clearance — toxicity risk higher
Renal impairmentDose reduced per GFRSpecialist supervision required
ChildPaediatric weight-based dosePaediatric cardiologist only

The information in this guide is for educational purposes only. Always confirm the dose with your doctor or pharmacist.

Frequently Asked Questions

Digoxin ki kitni dose leni chahiye?

The dose of Lanoxin (Digoxin) is strictly individualized — the doctor sets it based on renal function, age, body weight, and serum digoxin level. Typical adult maintenance is 0.125mg–0.25mg once daily, but the dose should never be decided on your own.

Agar Digoxin ki dose bhool jaye to kya karein?

Take it as soon as you remember. If the next dose is close, skip that dose. Never take a double dose — a double dose of Digoxin can be dangerous.

Digoxin overdose ke signs kya hain?

Signs of Digoxin overdose: severe bradycardia, irregular heartbeat, yellow/green halo vision (xanthopsia), severe nausea/vomiting, and confusion. This is a medical emergency — go to hospital immediately.

Elderly patients mein Digoxin ki dose alag kyon hoti hai?

Kidney function naturally decreases with age in elderly patients — the clearance of Digoxin is reduced. As a result, a lower dose is often required and monitoring must be done more closely to avoid toxicity.

Kya kidney (renal) patients Digoxin le sakte hain?

Digoxin must be used very cautiously in renal impairment — the kidneys eliminate Digoxin, so the dose can accumulate. The doctor will reduce the dose and monitor serum levels more frequently.

Brand alternatives, same-class options, and other medicines used for the same conditions as Lanoxin Tablet (Digoxin).

Sources

  1. DRAP Registered Products Database Drug Regulatory Authority of Pakistan
  2. WHO Model List of Essential Medicines, 23rd ed. (2023) World Health Organization
  3. British National Formulary (BNF) BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.