Mirtazep (Mirtazapine) Dosage Guide in Pakistan

Taking the correct dose of Mirtazapine (Mirtazep) is essential for successful treatment. Adjusting the dose yourself or stopping it abruptly can be unsafe. Always follow your doctor's advice.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-06-17

Dosage Guide

Quick Answer

The dose of Mirtazep (Mirtazapine) is determined by a doctor — typically starting at 15mg and increasing to 30mg or 45mg, taken at bedtime. Do not stop or adjust the dose yourself. Take a missed dose as soon as remembered; if the next dose is close, skip it — never take a double dose.

Dose at a Glance

Adult Dose

As prescribed by your doctor (typically 15mg–45mg once daily at bedtime)

Once daily — at bedtime (before sleeping at night)

Max: 45mg per day — do not exceed without a doctor's advice

Child Dose (Approved for those 18 and above; under 18 — specialist only)

Under specialist supervision only — routine use not recommended in under-18s

As directed by specialist

Missed Dose

If you miss a dose, take it as soon as you remember. If the next dose is close, skip it. Never take a double dose.

Overdose

In case of overdose, contact a doctor or emergency room immediately. Mirtazapine overdose can cause severe drowsiness, confusion, and serious cardiac effects.

Mirtazep (Mirtazapine) Dosage

Mirtazep (Mirtazapine) dose is always determined by a doctor. The guide below is for reference — confirm the actual dose with your doctor.

Adult Dose

As prescribed by your doctor
Typically: 15mg at night (starting), then increasing to 30mg or 45mg
Once daily — at bedtime (before sleeping)
Max: 45mg per day — do not exceed without a doctor's advice

Starting Dose: As per doctor's advice (commonly 15mg once at bedtime)

Usual Dose: As per doctor's advice (15mg–45mg at bedtime)

Max Daily Dose: 45mg — do not exceed without a doctor's advice

Child Dose

Mirtazapine is not recommended for routine use in those under 18 — only under specialist supervision.

How to Take

Once daily — at bedtime
Same time every day — for consistent blood levels
With or without food — both are acceptable
If stomach upset occurs, taking it after food is preferable

Best Time to Take

At bedtime (before sleeping) — use the sedative effect for sleep
Same time daily to maintain a routine

With Food or Empty Stomach

Both are acceptable. If stomach irritation occurs, take after food.

Missed Dose

If you miss a dose, take it as soon as you remember. If the next dose is close, skip the missed dose. Never take a double dose.

Overdose

Overdose may cause severe drowsiness, confusion, and cardiac issues. Contact the emergency room or a doctor immediately.

> Warning: Stopping Mirtazapine abruptly is unsafe. Taper only under a doctor's guidance.

Dose Summary Table

Patient	Dose	Notes
Adult	As per doctor's advice (15mg–45mg)	Once daily at bedtime
Under 18	Specialist only	Routine use not recommended

The information in this guide is for educational purposes only. Always confirm the dose with your doctor or pharmacist.

Frequently Asked Questions

Mirtazapine ki dose kitni hoti hai?

Mirtazapine is taken as per a doctor's advice — typically starting at 15mg and going up to 30mg or 45mg at bedtime. The doctor decides the dose based on the patient's condition.

Kya dose miss hone par double dose le sakte hain?

No — never take a double dose. If a dose is missed, take it as soon as remembered; if the next dose is close, skip it and resume at the next scheduled dose.

Kya Mirtazapine khane ke sath leni chahiye?

Mirtazapine can be taken with or without food. If stomach discomfort occurs, taking it after food is preferable. It should be taken at bedtime.

Mirtazapine kitni der mein kaam karna shuru karta hai?

A difference in sleep may be noticeable within the first week. The full antidepressant effect generally appears within 2–4 weeks. Do not stop without a doctor's advice.

Mirtazapine achanak band kar dein to kya hoga?

Stopping abruptly can cause withdrawal symptoms and a return of depression. Taper only under a doctor's guidance — reducing the dose is also the doctor's responsibility.

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Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.