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Stemetil (Prochlorperazine) Uses in Pakistan

Stemetil (Prochlorperazine) is commonly prescribed in Pakistan for nausea, vomiting, dizziness (vertigo), and migraine-associated nausea. This guide covers all its uses, indications, and important information.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated:

Uses

Quick Answer

Stemetil (Prochlorperazine) is used in Pakistan for nausea and vomiting, vertigo and labyrinthine disorders (dizziness), migraine-associated nausea, and short-term anxiety. It is a Phenothiazine class Rx medicine — do not take without a doctor's prescription.

Primary Uses at a Glance

Nausea and Vomiting (Ulti — Antiemetic)

Prochlorperazine blocks D2 dopamine receptors in the chemoreceptor trigger zone (CTZ — vomiting centre) — this stops nausea and vomiting. This is the most common use in Pakistan.

Short-term — as per doctor's prescription. Typically 5mg-10mg 2-3 times daily.

Vertigo and Labyrinthine Disorders (Chakkar Aana)

Prochlorperazine is a vestibular suppressant — it dampens abnormal signals from the inner ear and provides relief from dizziness. It is effective for vestibular vertigo and labyrinthine disorders.

5mg 3 times daily initially — specialist review is necessary for long-term use.

Migraine-Associated Nausea

Prochlorperazine provides antiemetic cover for nausea and vomiting accompanying migraine attacks — analgesic absorption is improved and overall migraine management is better.

As prescribed — per doctor's instructions.

Short-Term Anxiety (Adjunct)

Prochlorperazine is sometimes used as an adjunct in short-term anxiety management — however it is not a first-line anxiolytic. Under doctor's supervision only.

Per doctor's instructions — short-term only.

Schizophrenia / Psychosis (Specialist Use)

At 25mg dosing prochlorperazine has an antipsychotic effect via mesolimbic D2 blockade. However this use is now less common due to the availability of newer antipsychotics. Only on specialist prescription.

Only on psychiatrist prescription — 25mg dosing.

Other Uses

  • Migraine-associated nausea
  • Short-term anxiety (adjunct)

Stemetil (Prochlorperazine) Uses (Fayde / Kis kaam aata hai)

Stemetil contains Prochlorperazine — it belongs to the Phenothiazine / Antiemetic / Antipsychotic group. Below are all approved and common uses in Pakistan.

Primary Uses (Mukhya Istemal)

  • Nausea and Vomiting (Ulti) — D2 blockade in the chemoreceptor trigger zone (CTZ) stops nausea and vomiting
  • Vertigo and Labyrinthine Disorders (Chakkar Aana) — vestibular suppressant effect; dampens inner ear signals
  • Migraine-Associated Nausea — provides antiemetic cover during migraine attacks
  • Short-term Anxiety (Adjunct) — limited, doctor supervised use
  • Schizophrenia / Psychosis — 25mg dosing — specialist prescription only

How Prochlorperazine Works (Kaise Kaam Karta Hai)

Prochlorperazine is a D2 dopamine receptor antagonist — dopamine signalling in the vomiting centre (CTZ) is blocked → nausea and vomiting are suppressed. The vestibular suppressant effect provides relief from dizziness. Anticholinergic and antihistamine effects are also present. At higher doses mesolimbic D2 blockade produces an antipsychotic effect.

Who Should Take It (Kin Logon Ke Liye)

  • Adults with acute nausea/vomiting requiring short-term antiemetic
  • Patients with vestibular vertigo diagnosed by a doctor
  • Migraine patients with prominent nausea component
  • Adults under specialist care for anxiety or psychosis

When NOT to Use (Kab Nahi Leni Chahiye)

  • Parkinson's disease patients — dopamine blockade worsens symptoms
  • Motion sickness — scopolamine or cinnarizine preferred
  • Long-term self-medication without specialist review
  • Known allergy to prochlorperazine or phenothiazines

Summary

Stemetil (Prochlorperazine) is prescribed in Pakistan for vomiting, dizziness, and migraine nausea. Short-term use only — per doctor's instructions — long-term use carries a risk of tardive dyskinesia. Always consult a doctor.

The information in this guide is for educational purposes only.

Frequently Asked Questions

Stemetil / Prochlorperazine kis cheez ke liye use hoti hai?

Stemetil (Prochlorperazine) is used for nausea, vomiting, vertigo (dizziness), and migraine-associated vomiting. It is an Rx medicine — do not take without a doctor's prescription.

Kya Prochlorperazine vertigo ke liye effective hai?

Yes — prochlorperazine is effective for vestibular vertigo. However, betahistine is more preferred for Meniere's disease. Get diagnosis confirmed by a doctor.

Kya Stemetil sirf ulti ki dawa hai?

No — Stemetil's primary use is antiemetic but it is also used for vertigo, migraine nausea, and anxiety under specialist supervision.

Prochlorperazine motion sickness ke liye use ho sakti hai?

No — prochlorperazine is not indicated for motion sickness. Scopolamine (hyoscine) or cinnarizine is more appropriate for motion sickness.

Stemetil kitne waqt ke liye le sakte hain?

Stemetil is for short-term use. Long-term use carries a risk of tardive dyskinesia. Do not use long-term without a doctor's instructions.

Related medicines

Brand alternatives, same-class options, and other medicines used for the same conditions as Stemetil Tablet.

Other antiemetics (anti-vomiting)

Sibling medicines in the Antiemetics (Anti-Vomiting) class.

All in class →

Used for the same conditions

Other medicines commonly used for headache and overlapping conditions.

Headache hub →

Sources

  1. DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
  2. WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
  3. British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.