Solifenacin Tablet: Uses, Dosage & Side Effects in Pakistan

Solifenacin Tablet Uses, Dosage, Side Effects & Price in Pakistan

1. Quick Info (Mukhtasir Maloomat)

2. What is Solifenacin Tablet? (Solifenacin Tablet kya hai)

Solifenacin Tablet (brand: Vesicare) is used in Pakistan for overactive bladder (OAB) on a doctor's prescription. It belongs to the Antimuscarinic / Anticholinergic drug class and Solifenacin Succinate is its active ingredient.

It selectively blocks M3 muscarinic receptors in the smooth muscle (detrusor) of the bladder, preventing excessive contractions — thereby reducing urinary frequency, urgency, and urge incontinence. It is an Rx medicine — do not take without a doctor's prescription.

3. Uses (Fayde / Kis kaam aati hai)

• Overactive Bladder (OAB — peshaab baar baar aana, urinary urgency)
• Urge urinary incontinence
• Urinary frequency reduction
• Detrusor overactivity

4. Who Should Take (Kis ko leni chahiye)

• Adults diagnosed with overactive bladder (OAB) by a doctor
• Patients with urinary urgency and frequency affecting daily activities
• Patients with urge urinary incontinence
• Patients where non-pharmacological options (pelvic floor exercises, bladder training) have not been sufficient

5. When NOT to Take (Kab nahi leni chahiye)

• Narrow-angle glaucoma ho — CONTRAINDICATED
• Urinary retention or severe bladder outflow obstruction
• Severe GI conditions (toxic megacolon, myasthenia gravis)
• Severe renal or hepatic impairment
• Allergy to Solifenacin or any of its ingredients

6. Dosage (Kitni leni hai)

• As prescribed — typically 5mg once daily

• 5mg once daily; the doctor may increase to 10mg once daily if tolerated

• 10mg once daily — do not exceed the recommended limit

• If you miss a dose, take it as soon as you remember. If the next dose is close, skip the missed dose. Never take a double dose.

7. How to Take (Kaise leni hai)

• Once daily — taking at the same time is preferable

• Same time routine banayein

• Morning preferred

• With or without food; swallow the tablet whole, do not break it

8. Best Time (Kab leni chahiye)

• Morning — easier to remember the dose

• Daily same time

9. Empty Stomach or After Food (Khali pait ya khane ke baad)

• Solifenacin can be taken with or without food — food does not significantly affect absorption. If the stomach is sensitive, taking it after food is preferable.

10. Warnings (Ihtiyat)

• Narrow-angle glaucoma — CONTRAINDICATED
• Urinary retention or severe bladder outflow obstruction
• Men with BPH (enlarged prostate) — serious risk of acute urinary retention; be sure to discuss with your doctor
• Prolonged outdoor activity in Pakistan summers — solifenacin reduces sweating and increases heat stroke risk
• Elderly patients — consult your doctor about the risk of cognitive impairment and dementia with long-term anticholinergic use

11. Precautions (Ahm ehtiyaat)

• Store in a cool, dry place — below 30°C
• Keep away from direct sunlight
• Keep out of the reach of children
• Exercise caution when driving or operating machinery — blurred vision and dizziness may occur

12. Side Effects (Nuksanat)

• Dry mouth, Constipation, Blurred vision, Dizziness, Dry eyes

• Acute urinary retention (medical emergency — especially men with BPH), Severe constipation / paralytic ileus, Heat stroke (reduced sweating), QT prolongation (rare high doses), Cognitive impairment (elderly long-term use)

13. Drug Interactions (Dawaon ke sath reaction)

• CYP3A4 inhibitors such as ketoconazole or clarithromycin increase solifenacin blood levels — dose reduction may be needed
• Other antimuscarinic drugs (tolterodine, oxybutynin) cause additive anticholinergic burden — avoid combination
• Additive QT risk with QT-prolonging drugs
• With slow-release potassium chloride (KCl) tablets, slowed GI motility increases the risk of mucosal damage

When anticholinergic burden is excessive — the risk of confusion, urinary retention, and constipation increases, especially in the elderly.

14. When to See Doctor (Kab doctor ke paas jayein)

• Complete inability to urinate (acute urinary retention — EMERGENCY)
• Chest pain or palpitations (rare QT effect)
• Severe constipation or abdominal distension
• Confusion or memory impairment in the elderly (anticholinergic cognitive effect)
• Sudden eye pain or redness (possible glaucoma attack — EMERGENCY)

15. Alternatives (Sasti Dusri Dawaein)

16. Price in Pakistan (Price kitni hai)

17. FAQs (Aksar poochay jane walay sawalat)

Q: Solifenacin kis kaam aata hai?

A: Solifenacin (Vesicare) is used for overactive bladder (OAB) — it reduces urinary frequency, urgency, and urge incontinence. Do not take without a doctor's advice.

Q: Solifenacin ke side effects kya hain?

A: Common side effects include dry mouth, constipation, blurred vision, and dizziness. In men with BPH there is a risk of urinary retention. See a doctor immediately for any severe symptom.

Q: Solifenacin OAB mein kaise madad karta hai?

A: Solifenacin blocks M3 muscarinic receptors in the bladder, which prevents excessive contractions of the detrusor muscle — reducing urinary frequency and urgency.

Q: Solifenacin Pakistan mein price kya hai?

A: Price varies by pharmacy and city. For the updated price, confirm at a local pharmacy or on dawaai.pk.

Q: Solifenacin mard mein safe hai?

A: In men with BPH (enlarged prostate), solifenacin carries a serious risk of acute urinary retention. Be sure to inform your doctor of BPH history before starting this medicine.

18. Medical Review (Medical jaiza)

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-06-17

19. Disclaimer (Zaroori tanbeeh)

The information on this page is for awareness only. It is not medical advice. Always consult your doctor or pharmacist before taking any medicine. PakVita is not responsible for any harm.