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Ibuprofen vs Paracetamol: Ibuprofen vs Paracetamol — Generic-Level Comparison

At a generic level, this is the most-asked painkiller question worldwide. Paracetamol works in the brain to reduce fever and pain. Ibuprofen is an NSAID — pain, fever, AND inflammation, with more side effects.

Ib

Ibuprofen

Ibuprofen

VS
Pa

Paracetamol

Paracetamol

FeatureIbuprofenParacetamol
Drug classNSAIDAnalgesic / Antipyretic
How it worksBlocks COX enzymes (peripheral)Acts mostly in the brain
Pain relief✅ Strong, esp. inflammatory pain✅ Effective for general pain
Fever✅ Effective✅ Very effective
Inflammation✅ Strong❌ No effect
Period pain⚠️ Mild
Joint pain⚠️ Mild
Stomach side effects⚠️ Higher✅ Very low
Kidney effect⚠️ Avoid in CKD✅ Generally safe
Liver effect (overdose)Less⚠️ Severe with overdose
Pregnancy❌ Avoid in 3rd trimester✅ First-line
Children✅ Weight-based dose✅ Weight-based dose
Take with food✅ RequiredNot required
Common Pakistani brandsBrufen, Profen, InflamPanadol, Calpol, Paracet

Hamare expert ka khayal (Verdict)

For fever or simple pain, start with paracetamol — fewer side effects. For inflammatory pain (joints, period, sports injury), ibuprofen is more effective. They can be taken together for severe pain under medical advice. Don't exceed maximum daily doses: paracetamol 4g/day, ibuprofen 1.2g/day OTC (2.4g with doctor).

Disclaimer: Ye comparison sirf educational purposes ke liye hai. Koi bhi dawa lene se pehle apne doctor ya pharmacist se zaroor milein.