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Ponstan vs Synflex: Mefenamic Acid vs Naproxen — For Period & Joint Pain
Ponstan (Mefenamic Acid) is widely used in Pakistan for period pain. Synflex (Naproxen) is a longer-acting NSAID often preferred for joint pain and back pain. Both are NSAIDs and share class side effects.
Po
Ponstan
Mefenamic Acid 250mg
Sy
Synflex
Naproxen Sodium 275mg
FeaturePonstanSynflex
Generic (Salt)Mefenamic Acid 250mgNaproxen Sodium 275mg
Drug classNSAID (Fenamate)NSAID (Propionic acid)
Duration of one dose~6 hours~12 hours
Period pain (Mahawari)✅ First-line✅ Equally effective
Joint pain / arthritis⚠️ Less preferred✅ Preferred
Back pain⚠️ Less preferred✅ Preferred
Stomach ulcer risk⚠️ Higher⚠️ Lower than ibuprofen at high dose
Cardiovascular safetyModerate✅ Best NSAID for CV-risk patients
For elderly⚠️ Avoid⚠️ Use lowest effective dose
Pregnancy (3rd trimester)❌ Avoid❌ Avoid
Price (approx)Rs. 55–150Rs. 80–220
Hamare expert ka khayal (Verdict)
For short-course period pain, Ponstan (Mefenamic Acid) remains the Pakistani standard. For chronic joint or back pain, Synflex (Naproxen) — twice-daily dosing and a better cardiovascular safety profile — is generally preferred. Both must be taken after food.
Disclaimer: Ye comparison sirf educational purposes ke liye hai. Koi bhi dawa lene se pehle apne doctor ya pharmacist se zaroor milein.