Isosorbide Dinitrate Isdn — brands & medicines in Pakistan
Pakistan mein Isosorbide Dinitrate Isdn ke 1 brands available hain. Drug class: Nitrate. Neeche se koi bhi brand select karein aur uses, dosage, side effects aur price dekhein.
Quick Answer
Isosorbide Dinitrate Isdn is a nitrate used in Pakistan for Angina pectoris prophylaxis, Acute angina relief — sublingual 5mg tablet (faster onset), Left ventricular failure (adjunct therapy). Available as 1 brand. Prescription required. Always confirm dose with a doctor or pharmacist.
What is Isosorbide Dinitrate Isdn?
Isosorbide Dinitrate Isdn is a nitrate used in Pakistan for a range of medical conditions. Doctors and pharmacists in Pakistan recognize Isosorbide Dinitrate Isdn under multiple brand names — currently 1 listed on PakVita (1 tablet). The information below is a synthesis from DRAP-registered medicine entries, BNF, and WHO Essential Medicines references.
Common indications
- Angina pectoris prophylaxis
- Acute angina relief — sublingual 5mg tablet (faster onset)
- Left ventricular failure (adjunct therapy)
- Oesophageal spasm (off-label)
Indication and dose vary by medical condition, age, weight, and other factors. Always confirm with a qualified doctor or pharmacist before starting.
Typical dosage
As prescribed — multiple daily dosing required with nitrate-free interval; sublingual tablet (5mg) placed under tongue for acute angina
This is a general adult guidance pattern based on the manufacturer's label for one of the Isosorbide Dinitrate Isdn brands listed below. Children, elderly patients, pregnant women, and people with kidney or liver impairment usually need different dosing — confirm with your doctor.
Side effects
Common (usually mild)
- Headache (bukhaar jaisa dard — very common; usually improves after 1-2 weeks of use)
- Hypotension / dizziness (BP gir jaana — especially on standing)
- Flushing (skin laal hona)
- Reflex tachycardia
- Palpitations
- Nausea
Serious — stop and see a doctor
- Severe hypotension (especially with PDE5 inhibitors — potentially FATAL)
- Syncope / fainting (behoshi)
- Methaemoglobinaemia (rare — high dose — bluish skin, confusion)
Important warnings
- PDE5 inhibitors (sildenafil/Viagra, tadalafil/Cialis, vardenafil/Levitra, avanafil) ABSOLUTELY CONTRAINDICATED — severe or fatal hypotension can occur; never combine
- Riociguat (soluble guanylate cyclase stimulator) CONTRAINDICATED with all nitrates
- Nitrate tolerance — must maintain nitrate-free interval (10-12 hours overnight); asymmetric dosing required (e.g., 8AM and 1PM — NOT 8AM and 8PM)
- Headache — very common especially in first 1-2 weeks; usually improves with continued use
- Sit or lie down after first dose — hypotension and dizziness risk
- Alcohol increases hypotension risk — avoid
Conditions treated
Isosorbide Dinitrate Isdn brands in Pakistan (1)
Click any brand to see full uses, dosage, side effects, prices, and warnings.
Frequently asked questions
What is Isosorbide Dinitrate Isdn used for in Pakistan?
Isosorbide Dinitrate Isdn is commonly used for Angina pectoris prophylaxis, Acute angina relief — sublingual 5mg tablet (faster onset), Left ventricular failure (adjunct therapy), Oesophageal spasm (off-label). It belongs to the nitrate drug class.
What is the typical dosage of Isosorbide Dinitrate Isdn?
Typical adult dosing is described by manufacturers as: "As prescribed — multiple daily dosing required with nitrate-free interval; sublingual tablet (5mg) placed under tongue for acute angina". Always confirm dose, duration, and timing with a qualified doctor or pharmacist — dose depends on indication, weight, age, kidney/liver function, and other medications.
What are the common side effects of Isosorbide Dinitrate Isdn?
Common side effects include Headache (bukhaar jaisa dard — very common; usually improves after 1-2 weeks of use), Hypotension / dizziness (BP gir jaana — especially on standing), Flushing (skin laal hona), Reflex tachycardia, Palpitations, Nausea. Most are mild and resolve as the body adjusts. Stop the medicine and contact a doctor if side effects are severe, persistent, or include allergic symptoms (rash, swelling, breathing difficulty).
When should I stop Isosorbide Dinitrate Isdn and see a doctor?
Stop Isosorbide Dinitrate Isdn and seek urgent medical care if you experience: Severe hypotension (especially with PDE5 inhibitors — potentially FATAL); Syncope / fainting (behoshi); Methaemoglobinaemia (rare — high dose — bluish skin, confusion). These are serious signs that need immediate attention.
Is Isosorbide Dinitrate Isdn available without a prescription in Pakistan?
Prescription required.
What brands of Isosorbide Dinitrate Isdn are available in Pakistan?
1 brand of Isosorbide Dinitrate Isdn is listed on PakVita: 1 tablet. Browse the brand list below and click any name for prices, dosage, and full information.
Sources
- DRAP Registered Drug Products Database — Drug Regulatory Authority of Pakistan
- British National Formulary (BNF) — BMJ Group & Pharmaceutical Press
- WHO Model List of Essential Medicines, 23rd ed. — World Health Organization