Phenytoin — brands & medicines in Pakistan
Pakistan mein Phenytoin ke 1 brands available hain. Drug class: Anticonvulsant (Hydantoin). Neeche se koi bhi brand select karein aur uses, dosage, side effects aur price dekhein.
Quick Answer
Phenytoin is a anticonvulsant (hydantoin) used in Pakistan for Epilepsy — tonic-clonic seizures (grand mal — dora, fits), Partial seizures (focal seizures), Status epilepticus (IV — emergency). Available as 1 brand. Prescription required. Always confirm dose with a doctor or pharmacist.
What is Phenytoin?
Phenytoin is a anticonvulsant (hydantoin) used in Pakistan for a range of medical conditions. Doctors and pharmacists in Pakistan recognize Phenytoin under multiple brand names — currently 1 listed on PakVita (1 capsule). The information below is a synthesis from DRAP-registered medicine entries, BNF, and WHO Essential Medicines references.
Common indications
- Epilepsy — tonic-clonic seizures (grand mal — dora, fits)
- Partial seizures (focal seizures)
- Status epilepticus (IV — emergency)
- Trigeminal neuralgia (off-label)
Indication and dose vary by medical condition, age, weight, and other factors. Always confirm with a qualified doctor or pharmacist before starting.
Typical dosage
As prescribed only — dose individualized by serum phenytoin level monitoring (target 10–20 mg/L); zero-order kinetics — small dose changes can cause disproportionate level changes; never self-adjust dose
This is a general adult guidance pattern based on the manufacturer's label for one of the Phenytoin brands listed below. Children, elderly patients, pregnant women, and people with kidney or liver impairment usually need different dosing — confirm with your doctor.
Side effects
Common (usually mild)
- Nystagmus
- Ataxia
- Diplopia (dobli nazar)
- Sedation / drowsiness
- Gingival hyperplasia
- Hirsutism
Serious — stop and see a doctor
- Stevens-Johnson Syndrome (SJS) / DRESS — life-threatening rash / blistering — stop immediately + EMERGENCY
- Hepatotoxicity (liver damage)
- Peripheral neuropathy (long-term)
- Osteomalacia / osteoporosis (vitamin D deficiency — CYP enzyme induction)
Important warnings
- NARROW THERAPEUTIC INDEX — serum level monitoring is essential; the difference between therapeutic and toxic dose is very small
- ZERO-ORDER KINETICS — even a small dose change can disproportionately raise the level — toxicity can occur
- DO NOT STOP ABRUPTLY — tapering is essential; sudden discontinuation can cause seizures
- WIDESPREAD RASH / BLISTERS — stop immediately — Stevens-Johnson Syndrome (SJS) / DRESS — life-threatening emergency
- PREGNANCY CATEGORY D — teratogenic (fetal hydantoin syndrome, neural tube defects) — consult neurologist
- EXTENSIVE DRUG INTERACTIONS — serious interactions with TB drug isoniazid, fluconazole, and many other medicines
Phenytoin brands in Pakistan (1)
Click any brand to see full uses, dosage, side effects, prices, and warnings.
Frequently asked questions
What is Phenytoin used for in Pakistan?
Phenytoin is commonly used for Epilepsy — tonic-clonic seizures (grand mal — dora, fits), Partial seizures (focal seizures), Status epilepticus (IV — emergency), Trigeminal neuralgia (off-label). It belongs to the anticonvulsant (hydantoin) drug class.
What is the typical dosage of Phenytoin?
Typical adult dosing is described by manufacturers as: "As prescribed only — dose individualized by serum phenytoin level monitoring (target 10–20 mg/L); zero-order kinetics — small dose changes can cause disproportionate level changes; never self-adjust dose". Always confirm dose, duration, and timing with a qualified doctor or pharmacist — dose depends on indication, weight, age, kidney/liver function, and other medications.
What are the common side effects of Phenytoin?
Common side effects include Nystagmus, Ataxia, Diplopia (dobli nazar), Sedation / drowsiness, Gingival hyperplasia, Hirsutism. Most are mild and resolve as the body adjusts. Stop the medicine and contact a doctor if side effects are severe, persistent, or include allergic symptoms (rash, swelling, breathing difficulty).
When should I stop Phenytoin and see a doctor?
Stop Phenytoin and seek urgent medical care if you experience: Stevens-Johnson Syndrome (SJS) / DRESS — life-threatening rash / blistering — stop immediately + EMERGENCY; Hepatotoxicity (liver damage); Peripheral neuropathy (long-term); Osteomalacia / osteoporosis (vitamin D deficiency — CYP enzyme induction). These are serious signs that need immediate attention.
Is Phenytoin available without a prescription in Pakistan?
Prescription required.
What brands of Phenytoin are available in Pakistan?
1 brand of Phenytoin is listed on PakVita: 1 capsule. Browse the brand list below and click any name for prices, dosage, and full information.
Sources
- DRAP Registered Drug Products Database — Drug Regulatory Authority of Pakistan
- British National Formulary (BNF) — BMJ Group & Pharmaceutical Press
- WHO Model List of Essential Medicines, 23rd ed. — World Health Organization