Centrum Tablet Side Effects in Pakistan

A complete guide to the side effects of Centrum Tablet. From common effects to serious warnings — everything you need to know is on this page.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-06-21

Side Effects

Quick Answer

Common side effects of Centrum Tablet include nausea and stomach upset, especially if taken on an empty stomach. Serious effects such as severe allergic reaction or signs of vitamin toxicity require immediate medical attention. Most adults tolerate Centrum Tablet well when taken with food at the recommended dose. Contact your doctor if any side effect persists or worsens.

Side Effects at a Glance

Common

Nausea (especially if taken on an empty stomach)
Constipation
Stomach upset or mild abdominal discomfort

Serious — See a Doctor

Severe allergic reaction (rash, hives, facial swelling, difficulty breathing)
Signs of vitamin A toxicity: headache, blurred vision, nausea, bone pain (with prolonged high-dose use)
Signs of vitamin D toxicity: confusion, fatigue, excessive thirst, kidney problems (rare at standard doses)

When to See a Doctor Immediately

Difficulty breathing or throat swelling after taking the tablet
Severe skin rash or hives
Persistent or worsening headache, blurred vision, or dizziness

Centrum Tablet Side Effects (Nuksanat)

Centrum Tablet (Multivitamin + Minerals) is generally well tolerated when taken at the correct dose with food. However, like all supplements, it can cause side effects in some individuals.

Common Side Effects (Aam Nuksanat)

Nausea (especially if taken on an empty stomach)
Constipation
Stomach upset or mild abdominal discomfort

These side effects are usually mild and resolve when the tablet is taken with food. If they continue, inform your doctor.

Serious Side Effects (Sanjeedah Nuksanat)

Severe allergic reaction (rash, hives, facial swelling, difficulty breathing) — see a doctor immediately
Signs of vitamin A toxicity: headache, blurred vision, nausea, bone pain — see a doctor immediately
Signs of vitamin D toxicity: confusion, fatigue, excessive thirst — see a doctor immediately

When to See a Doctor (Kab Doctor Se Milna Zaroori Hai)

Difficulty breathing or throat swelling after taking the tablet
Severe skin rash or hives
Persistent or worsening headache, blurred vision, or dizziness

Warnings and Precautions (Ihtiyat)

Don't use Centrum Tablet if you are allergic to any of its ingredients
Do not take more than the recommended dose; excess fat-soluble vitamins can accumulate and cause harm
Keep out of reach of children

Side Effects Summary Table

Type	Side Effect	Action
Common	Nausea	Take with food
Common	Constipation	Stay hydrated; inform doctor if persistent
Common	Stomach upset	Take with food
Serious	Severe allergic reaction	Stop use; see a doctor immediately
Serious	Signs of vitamin toxicity	Stop use; see a doctor immediately

Reporting Side Effects

If you notice any unexpected side effect, report it on the DRAP pharmacovigilance portal: https://www.dra.gov.pk/pharmacovigilance

The information in this guide is for educational purposes only. If you notice any side effect, contact your doctor or pharmacist.

Frequently Asked Questions

What are the most common side effects of Centrum Tablet?

The most commonly reported side effects of Centrum Tablet include nausea and stomach upset, particularly when taken on an empty stomach. Taking the tablet with food usually prevents these effects.

Can Centrum Tablet cause allergic reactions?

Yes, like all medicines and supplements, Centrum Tablet can cause allergic reactions in some people. Signs include rash, itching, swelling, or difficulty breathing. Stop use and seek medical help immediately.

Is Centrum Tablet safe to take for a long time?

Long-term daily use at the recommended dose (1 tablet per day) is generally considered safe. The risk of vitamin toxicity arises only with doses significantly above the label recommendation.

What should I do if I experience side effects from Centrum Tablet?

For mild side effects such as nausea, take the tablet with food. For serious effects such as a severe allergic reaction, stop the supplement and contact your doctor immediately.

Does Centrum Tablet affect the liver or kidneys?

At the standard dose, Centrum Tablet is not known to cause liver or kidney problems in healthy adults. Patients with existing kidney disease should consult their doctor before taking any multivitamin containing fat-soluble vitamins or minerals such as potassium.

Brand alternatives, same-class options, and other medicines used for the same conditions as Centrum Tablet.

Other supplements and vitamins

Sibling medicines in the Supplements and Vitamins class.

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Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.