Combantrin Suspension: Uses, Dosage & Side Effects in Pakistan

Combantrin Suspension Uses, Dosage, Side Effects & Price in Pakistan

1. Quick Info (Mukhtasir Maloomat)

2. What is Combantrin Suspension? (Combantrin Suspension kya hai)

Combantrin Suspension contains pyrantel pamoate, an anthelmintic agent that works by acting as a depolarising neuromuscular blocker in susceptible nematodes (intestinal worms). It causes a sudden and sustained muscle spasm in the worm by binding to nicotinic acetylcholine receptors, leading to paralysis of the parasite. Once paralysed, the worm is unable to maintain its grip on the intestinal wall and is expelled from the body through normal bowel movement. Pyrantel is poorly absorbed from the gastrointestinal tract, concentrating its action locally within the intestine where the parasites live.

Combantrin Suspension is one of several anthelmintic options available in Pakistan and is particularly suitable for community-level treatment of common intestinal worm infestations due to its OTC availability, good tolerability, and single-dose convenience for most indications. Always use Combantrin Suspension as directed by your doctor or pharmacist.

3. Uses (Fayde / Kis kaam aati hai)

• Pinworm (Enterobius vermicularis) infections
• Roundworm (Ascaris lumbricoides) infections
• Mixed intestinal worm infections in children and adults

4. Who Should Take (Kis ko leni chahiye)

• Children and adults with confirmed intestinal worm infections (pinworms, roundworms)
• Family members of an infected person (simultaneous treatment is often recommended)
• Patients with mixed worm infestations as directed by a doctor

5. When NOT to Take (Kab nahi leni chahiye)

• Known allergy to Pyrantel Pamoate or any ingredient
• Severe liver disease — consult a doctor before use
• Do not use concurrently with piperazine-based antiparasitics

6. Dosage (Kitni leni hai)

• As per pack label or as directed by a doctor or pharmacist

• If you miss a dose, take it as soon as you remember. If the next dose is close, skip the missed dose. Never take a double dose.

7. How to Take (Kaise leni hai)

• Shake the suspension well before use. Measure the dose accurately using the included measuring device. Can be taken with or without food.

8. Warnings (Ihtiyat)

• Do not use Combantrin Suspension if you are allergic to Pyrantel Pamoate
• Use with caution in patients with liver disease

9. Storage (Rakhne ka tareeqa)

• Below 25 degrees Celsius. Do not freeze. Protect from direct sunlight.
• Keep away from direct sunlight and moisture
• Keep out of the reach of children

10. Side Effects (Nuksanat)

• Mild nausea or stomach discomfort
• Diarrhoea
• Headache

• Severe liver enzyme elevation with prolonged or high-dose use (rare) — consult a doctor if jaundice or unusual fatigue develops — see a doctor immediately
• Severe allergic reaction in hypersensitive individuals — stop use and seek medical help immediately — see a doctor immediately

11. Drug Interactions (Dawaon ke sath reaction)

• Avoid concurrent use with piperazine compounds as they may antagonise the effect of Pyrantel Pamoate

12. When to See Doctor (Kab doctor ke paas jayein)

• Symptoms persist or worsen after treatment
• Severe abdominal pain or bloody stools
• Signs of allergic reaction (rash, swelling, difficulty breathing)

13. Alternatives (Dusri Dawaein)

14. Price in Pakistan (Price kitni hai)

(Note: Price depends on the pharmacy and pack size.)

15. FAQs (Aksar poochay jane walay sawalat)

Q: Combantrin Suspension kis kaam aati hai?

A: Combantrin Suspension contains Pyrantel Pamoate and is used to treat intestinal worm infections such as pinworms and roundworms in children and adults. Always follow the dosage instructions on the label or as directed by a doctor.

Q: Kitni baar deni chahiye?

A: A single dose is usually effective for pinworm and roundworm infections. A repeat dose after 2 to 3 weeks may be recommended. Always follow your doctor's advice.

Q: Pakistan mein price kitni hai?

A: Price depends on the pharmacy and city. Confirm the current rate at a local pharmacy or licensed online platform.

Q: Pregnancy mein safe hai?

A: Consult your doctor before using Combantrin Suspension during pregnancy. Safety in pregnancy has not been fully established.

Q: Nuksanat kya hain?

A: Side effects are usually mild and include nausea or stomach discomfort. Contact your doctor if symptoms are severe or persist.

16. Medical Review (Medical jaiza)

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-06-26

17. Disclaimer (Zaroori tanbeeh)

The information on this page is for awareness only. It is not medical advice. Always consult your doctor or pharmacist before taking any medicine. PakVita is not responsible for any harm.