Indapamide (Natrilix) Tablet Dosage Guide in Pakistan

Indapamide (Natrilix) dose is straightforward, but taking it in the morning and monitoring electrolytes are essential. This guide provides the adult dose, child guidance, and notes for special populations.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-06-17

Dosage Guide

Quick Answer

Indapamide (Natrilix) standard adult dose for hypertension is 1.5mg SR once daily in the morning. For oedema or stronger effect, 2.5mg once daily may be used. Always take in the morning to avoid night-time frequent urination. Do not exceed 2.5mg per day. Electrolyte (potassium, sodium) and renal function monitoring is required — especially in elderly patients.

Dose at a Glance

Adult Dose

1.5mg SR once daily (hypertension); 2.5mg once daily (oedema or stronger antihypertensive) — as prescribed

Once daily — morning

Max: 2.5mg per day — higher doses increase electrolyte loss without more BP benefit

Child Dose (Children — specialist only)

Not generally recommended — specialist guidance required

N/A

Missed Dose

If you miss a dose of indapamide, take it as soon as you remember — but if it is already late evening and you are concerned about night-time urination, wait until the next morning. Never take a double dose.

Overdose

Indapamide overdose can cause severe electrolyte imbalance (hypokalemia, hyponatraemia) and dehydration. If an overdose occurs, contact a doctor or emergency services IMMEDIATELY. Symptoms: severe dizziness, muscle weakness, confusion (especially in the elderly).

Indapamide (Natrilix) Tablet Dosage (Kitni leni hai)

Indapamide Tablet — should be taken once daily in the morning. The correct dosage and timing are essential for treatment success.

Adult Dose (Baalgon ke liye)

Hypertension (BP control): 1.5mg SR once daily — morning — preferred
Oedema / stronger antihypertensive: 2.5mg once daily — morning
Max daily dose: 2.5mg — higher doses increase diuresis but do not improve BP benefit; electrolyte loss increases

Starting Dose: 1.5mg SR once daily (morning)

Usual Dose: 1.5mg SR once daily (antihypertensive); 2.5mg once daily (oedema)

Max Daily Dose: 2.5mg per day

Child Dose (Bachon ke liye)

Indapamide is generally not recommended for children — only under specialist guidance.

How to Take (Kaise leni hai)

Once daily
Morning preferred — to avoid nocturnal diuresis and disrupted sleep
With or without food
Do not crush or chew the SR tablet — swallow whole (sustained release tablet)

Best Time to Take (Kab leni chahiye)

Morning — in the first part of the day
Same time daily to maintain a routine

With Food or Empty Stomach (Khali pait ya khane ke baad)

Indapamide is not affected by food — before or after food are both fine. If stomach upset occurs, take it with food.

Missed Dose (Dose chhoot jaye to kya karein)

Take it on the same day as soon as you remember. If it is already late evening or the next dose time is close, skip — never take a double dose.

Overdose (Zyada Dose)

Excessive dose can cause severe hypokalemia, hyponatraemia, and dehydration — contact a doctor or emergency services immediately. Symptoms: severe muscle weakness, confusion, cardiac arrhythmia.

Dose Summary Table

Indication	Dose	Timing
Hypertension	1.5mg SR once daily	Morning
Oedema	2.5mg once daily	Morning
Max per day	2.5mg	—
Child	Specialist only	—

Special Populations

Elderly: Higher risk of hyponatraemia — start low, monitor closely
Renal impairment: Mild-moderate — use with caution; severe — contraindicated
Hepatic impairment: Caution — risk with severe hepatic disease
Digoxin users: Monitor potassium closely — hypokalemia can cause digoxin toxicity

The information in this guide is for educational purposes only. Always confirm the dose with your doctor or pharmacist.

Frequently Asked Questions

Indapamide ki dose kitni hoti hai?

For hypertension, 1.5mg SR once daily in the morning is preferred. For oedema or a stronger antihypertensive effect, 2.5mg once daily is used. The doctor decides based on the condition.

Indapamide subah kyun leni chahiye?

Indapamide is a diuretic — taking it at night causes nocturnal urination which disrupts sleep. Taking it in the morning keeps daytime diuresis normal.

Indapamide 1.5mg SR aur 2.5mg mein kya farq hai?

1.5mg SR is sustained release — preferred for antihypertensive use, more vasodilatory, less diuresis. 2.5mg is a conventional tablet — for oedema or stronger BP reduction. Your doctor advises which to take.

Indapamide lete waqt potassium monitor karna kyun zaroori hai?

Indapamide causes the kidney to excrete potassium along with sodium. Low potassium (hypokalemia) can cause muscle cramps and cardiac arrhythmia — particularly dangerous in patients taking digoxin. Your doctor orders regular blood tests.

Indapamide kitne time tak leni hoti hai?

For hypertension, indapamide is usually a long-term (indefinite) medicine — to maintain blood pressure control. The doctor continues it with monitoring. Do not stop on your own.

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Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.