Motilium Tablet Side Effects in Pakistan

A complete guide to the side effects of Motilium Tablet. From common effects to serious warnings, including the important heart-rhythm caution, everything you need to know is on this page.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-07-02

Side Effects

Quick Answer

Common side effects of Motilium Tablet include dry mouth and headache. Serious effects such as irregular heartbeat require immediate medical attention, since domperidone carries a recognised risk of heart rhythm changes. Most patients tolerate Motilium Tablet well at the correct, short-term dose. Contact your doctor if any side effect persists or worsens.

Side Effects at a Glance

Common

Dry mouth
Headache
Abdominal cramps

Serious — See a Doctor

Irregular heartbeat
Fainting
Severe allergic reaction

When to See a Doctor Immediately

Irregular or rapid heartbeat
Fainting or severe dizziness
Swelling of the face, lips, or throat, or difficulty breathing

Motilium Tablet Side Effects (Nuksanat)

Motilium Tablet (Domperidone) is generally safe when taken at the correct, short-term dose under medical supervision. However, like all medicines, it can cause side effects in some patients, including a recognised heart-rhythm risk.

Common Side Effects (Aam Nuksanat)

Dry mouth
Headache
Abdominal cramps

These side effects are usually mild. If they continue, inform your doctor.

Serious Side Effects (Sanjeedah Nuksanat)

Irregular heartbeat — see a doctor immediately
Fainting — see a doctor immediately
Severe allergic reaction — see a doctor immediately

Domperidone is a well-documented case where regulatory bodies internationally have restricted its use because of the risk of serious heart rhythm changes, particularly with higher doses, longer courses, in older patients, or in people with existing heart or electrolyte problems. Doctors weigh this risk carefully before prescribing Motilium Tablet and typically limit it to short-term use.

When to See a Doctor (Kab Doctor Se Milna Zaroori Hai)

Irregular or rapid heartbeat
Fainting or severe dizziness
Swelling of the face, lips, or throat, or difficulty breathing

Warnings and Precautions (Ihtiyat)

Don't use Motilium Tablet if you are allergic to Domperidone or any ingredient
Avoid if you have a known heart rhythm problem (QT prolongation), significant electrolyte disturbance, or severe heart disease
Use with caution in elderly patients and those taking other medicines that can affect heart rhythm

Side Effects Summary Table

Type	Side Effect	Action
Common	Dry mouth	Monitor / inform doctor
Common	Headache	Monitor / inform doctor
Common	Abdominal cramps	Monitor / inform doctor
Serious	Irregular heartbeat	See a doctor immediately
Serious	Fainting	See a doctor immediately

Reporting Side Effects

If you notice any unexpected side effect, report it on the DRAP pharmacovigilance portal: https://www.dra.gov.pk/pharmacovigilance

The information in this guide is for educational purposes only. If you notice any side effect, contact your doctor or pharmacist.

Frequently Asked Questions

Motilium Tablet ke sabse aam nuksanat kya hain?

The most commonly reported side effects of Motilium Tablet include dry mouth and headache. These are usually mild and go away on their own. Inform your doctor if they persist.

Kya Motilium Tablet dil ki dhadkan par asar dal sakti hai?

Yes. Domperidone, the active ingredient in Motilium Tablet, carries a recognised risk of affecting heart rhythm (QT prolongation), especially at higher doses, in older patients, or with certain other medicines. This is why it is prescribed for the shortest effective duration and avoided in patients with existing heart or electrolyte problems.

Motilium Tablet lambay arsay tak lena safe hai?

Long-term safety depends on the condition and the patient. Your doctor will monitor for signs of heart rhythm changes if continued use is needed, and will decide whether long-term use is appropriate.

Motilium Tablet se side effect ho to kya karna chahiye?

For mild side effects, inform your pharmacist. For serious effects such as an irregular heartbeat or fainting, stop the medicine and contact your doctor immediately or go to the nearest hospital.

Kya Motilium Tablet liver ya kidney par asar karti hai?

Motilium Tablet may require dose adjustment or should be avoided in patients with liver impairment. Your doctor will advise based on your test results and overall health condition.

Brand alternatives, same-class options, and other medicines used for the same conditions as Motilium Tablet.

Brand alternatives

Other Domperidone brands available in Pakistan.

All brands →

Other antiemetics (anti-vomiting)

Sibling medicines in the Antiemetics (Anti-Vomiting) class.

All in class →

Used for the same conditions

Other medicines commonly used for stomach pain (abdominal pain) and overlapping conditions.

Stomach Pain (Abdominal Pain) hub →

Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.