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Progesterone Capsule Dosage Guide in Pakistan

Taking the correct dose of progesterone capsule is essential for treatment success. The dose differs by route (oral vs vaginal) and indication (IVF, miscarriage prevention, HRT). Always follow the guidance of your doctor or fertility specialist.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-06-17

Dosage Guide

Quick Answer

Progesterone capsule dosage is indication-specific and must be prescribed by a doctor. For IVF luteal support, 200–400mg vaginally per day is typical. For HRT, 100–200mg orally at bedtime. Oral progesterone (Utrogestan) causes significant sedation and must be taken at night with food. The vaginal route (Cyclogest) is preferred in pregnancy and IVF for better uterine bioavailability.

Dose at a Glance

Adult Dose

Indication-specific — 100–400mg/day (as prescribed)

Once or twice daily depending on indication and route; vaginal route typically 1–2 times daily

Max: As prescribed — do not exceed doctor's stated dose

Child Dose (Not applicable)

Not applicable — not used in children

Not applicable

Missed Dose

If you miss a dose, take it as soon as you remember. If the next dose is close, skip the missed dose. Never take a double dose. If a dose is missed during IVF, inform the clinic immediately — consistency in the IVF protocol is very important.

Overdose

Progesterone overdose most commonly causes excessive sedation, dizziness, and nausea. In the event of an excessive dose, contact a doctor immediately or go to the emergency room.

Progesterone Capsule Dosage (Kitni leni hai)

Correct dosage of Progesterone Capsule (Utrogestan/Cyclogest) is critical — the dose depends on your specific indication (IVF, miscarriage prevention, HRT) and route (oral or vaginal). Always follow your doctor's or clinic's prescription exactly.

Adult Dose (Baalgon ke liye)

IVF / Luteal Phase Support:

200–400mg/day vaginally (Cyclogest 200mg or 400mg suppositories, Crinone gel) — as prescribed by IVF clinic
Some protocols: 100–200mg orally at bedtime in addition to vaginal (combined approach)

Recurrent Miscarriage Prevention:

Typically 200–400mg/day vaginally or 200mg orally at bedtime — as prescribed

Hormone Replacement Therapy (HRT):

100mg or 200mg orally at bedtime (taken after fatty meal for better absorption)

Secondary Amenorrhoea / Luteal Phase Defect:

As prescribed — typically cyclically

Do not exceed the recommended limit — dose is indicator-specific

Starting Dose: As prescribed at IVF egg retrieval / embryo transfer day (for IVF) or as directed (for HRT)

Usual Dose: Indication-dependent (see above)

Max Daily Dose: As prescribed by doctor — do not exceed stated dose

Child Dose (Bachon ke liye)

Not applicable — Progesterone capsule is not used in children.

How to Take (Kaise leni hai)

Oral route (Utrogestan):

Take at bedtime — causes significant sedation
Take with food or after a fatty meal
Swallow the capsule whole

Vaginal route (Cyclogest suppository / Crinone gel):

Insert using the vaginal applicator as per pack instructions
Follow the clinic's protocol for route and timing

Best Time to Take (Kab leni chahiye)

Oral Utrogestan: At bedtime — the drowsiness side effect is managed
Vaginal route: Follow clinic protocol timing

With Food or Empty Stomach (Khali pait ya khane ke baad)

Oral Utrogestan — take with food. The vaginal route is independent of food.

Missed Dose (Dose chhoot jaye to kya karein)

If you miss a dose, take it as soon as you remember. If the next dose is close, skip the missed dose. Never take a double dose. If a dose is missed during IVF, inform the clinic immediately.

Overdose (Zyada Dose)

Excessive sedation, dizziness, and nausea can be signs of too high a dose. Contact a doctor or the nearest emergency room immediately.

Dose Summary Table

Indication	Route	Dose	Notes
IVF luteal support	Vaginal (preferred)	200–400mg/day	As per clinic protocol
Recurrent miscarriage	Vaginal or oral	200–400mg/day	Doctor prescribed
HRT (menopause)	Oral (at bedtime)	100–200mg/night	With fatty food
Secondary amenorrhoea	Oral or vaginal	As prescribed	Doctor prescribed

The information in this guide is for educational purposes only. Always confirm the dose with your doctor or pharmacist.

Frequently Asked Questions

Progesterone capsule IVF mein kitni dose leni hai?

In IVF, generally 200–400mg/day is given via the vaginal route, but the exact dose is decided by your IVF clinic's protocol. Do not change or stop the dose on your own — ask the clinic.

Oral progesterone lene ka sahi waqt kya hai?

Oral progesterone (Utrogestan) should be taken at bedtime — it causes drowsiness. It should be taken with food or after a fatty meal.

Kya vaginal progesterone driving ke baad li ja sakti hai?

Vaginal route (Cyclogest) does not cause sedation like the oral route — sedation risk is only with the oral route. Follow clinic instructions for vaginal dose timing.

Agar IVF mein progesterone dose miss ho jaye to kya karein?

Call your IVF clinic immediately — consistency of progesterone in the IVF protocol is very important. The clinic will guide whether to complete the dose or skip it.

Progesterone kitni der tak leni hai pregnancy mein?

In most cases, progesterone is given until 12–16 weeks, after which the placenta begins producing its own progesterone. The doctor or clinic will provide the exact tapering schedule — do not stop on your own.

Brand alternatives, same-class options, and other medicines used for the same conditions as Progesterone Capsule (Utrogestan).

Other hormonal contraceptives & progestogens

Sibling medicines in the Hormonal Contraceptives & Progestogens class.

All in class →

Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.