Seroquel Side Effects in Pakistan

A complete guide to the side effects of Seroquel. From common effects to serious warnings — everything you need to know is on this page.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-07-02

Side Effects

Quick Answer

Common side effects of Seroquel include drowsiness and dry mouth. Serious effects such as neuroleptic malignant syndrome require immediate medical attention. Most patients tolerate Seroquel well at the correct dose. Contact your doctor if any side effect persists or worsens.

Side Effects at a Glance

Common

Drowsiness or sedation
Dry mouth
Dizziness
Weight gain and increased appetite

Serious — See a Doctor

Neuroleptic malignant syndrome (high fever, muscle rigidity, confusion)
Tardive dyskinesia (uncontrollable muscle movements)
Significant changes in blood sugar or cholesterol levels

When to See a Doctor Immediately

High fever, muscle stiffness, or confusion
New or worsening thoughts of self-harm or suicide
Uncontrollable, repetitive muscle movements of the face or body

Seroquel Side Effects (Nuksanat)

Seroquel (Quetiapine) is generally well tolerated when taken at the correct dose. However, like all medicines, it can cause side effects in some patients.

Common Side Effects (Aam Nuksanat)

Drowsiness or sedation
Dry mouth
Dizziness
Weight gain and increased appetite

These side effects are usually mild. If they continue, inform your doctor.

Serious Side Effects (Sanjeedah Nuksanat)

Neuroleptic malignant syndrome (high fever, muscle rigidity, confusion) — see a doctor immediately
Tardive dyskinesia (uncontrollable muscle movements) — see a doctor immediately
Significant changes in blood sugar or cholesterol levels — see a doctor immediately

When to See a Doctor (Kab Doctor Se Milna Zaroori Hai)

High fever, muscle stiffness, or confusion
New or worsening thoughts of self-harm or suicide
Uncontrollable, repetitive muscle movements of the face or body

Warnings and Precautions (Ihtiyat)

Don't use Seroquel if you are allergic to Quetiapine or any ingredient
Seroquel commonly causes sedation; avoid driving or operating machinery until you know how it affects you

Side Effects Summary Table

Type	Side Effect	Action
Common	Drowsiness or sedation	Monitor / inform doctor
Common	Dry mouth	Monitor / inform doctor
Common	Weight gain and increased appetite	Monitor / inform doctor
Serious	Neuroleptic malignant syndrome	See a doctor immediately
Serious	Tardive dyskinesia	See a doctor immediately

Reporting Side Effects

If you notice any unexpected side effect, report it on the DRAP pharmacovigilance portal: https://www.dra.gov.pk/pharmacovigilance

The information in this guide is for educational purposes only. If you notice any side effect, contact your doctor or pharmacist.

Frequently Asked Questions

What are the most common side effects of Seroquel?

The most commonly reported side effects of Seroquel include drowsiness and dry mouth. These are usually mild and may lessen over time. Inform your doctor if they persist.

Can Seroquel cause allergic reactions?

Yes, like all medicines, Seroquel can cause allergic reactions in some people. Signs include rash, itching, swelling, or difficulty breathing. Stop use and seek medical help immediately if this happens.

Is Seroquel safe to take for a long time?

Long-term safety depends on the condition and the patient. Your doctor will monitor for signs of tardive dyskinesia and metabolic changes, such as weight gain, blood sugar, or cholesterol changes, if continued use is needed.

What should I do if I experience side effects from Seroquel?

For mild side effects, inform your pharmacist. For serious effects such as neuroleptic malignant syndrome, stop the medicine and contact your doctor immediately or go to the nearest hospital.

Does Seroquel affect the liver or kidneys?

Seroquel may require dose adjustment in patients with liver or kidney impairment. Your doctor will advise based on your test results and overall health condition.

Brand alternatives, same-class options, and other medicines used for the same conditions as Seroquel Tablet.

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Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.