Letrozole — brands & medicines in Pakistan
Pakistan mein Letrozole ke 1 brands available hain. Drug class: Aromatase Inhibitor. Neeche se koi bhi brand select karein aur uses, dosage, side effects aur price dekhein.
Quick Answer
Letrozole is a aromatase inhibitor used in Pakistan for Hormone receptor-positive (HR+) breast cancer (postmenopausal — adjuvant/extended adjuvant/metastatic), Ovulation induction in PCOS and infertility (off-label — gynaecologist supervised), Endometriosis-associated infertility (off-label). Available as 1 brand. Prescription required. Always confirm dose with a doctor or pharmacist.
What is Letrozole?
Letrozole is a aromatase inhibitor used in Pakistan for a range of medical conditions. Doctors and pharmacists in Pakistan recognize Letrozole under multiple brand names — currently 1 listed on PakVita (1 tablet). The information below is a synthesis from DRAP-registered medicine entries, BNF, and WHO Essential Medicines references.
Common indications
- Hormone receptor-positive (HR+) breast cancer (postmenopausal — adjuvant/extended adjuvant/metastatic)
- Ovulation induction in PCOS and infertility (off-label — gynaecologist supervised)
- Endometriosis-associated infertility (off-label)
Indication and dose vary by medical condition, age, weight, and other factors. Always confirm with a qualified doctor or pharmacist before starting.
Typical dosage
As prescribed by oncologist or gynaecologist
This is a general adult guidance pattern based on the manufacturer's label for one of the Letrozole brands listed below. Children, elderly patients, pregnant women, and people with kidney or liver impairment usually need different dosing — confirm with your doctor.
Side effects
Common (usually mild)
- Hot flushes
- Arthralgia — joint pain
- Fatigue
- Headache
- Nausea
- Bone loss / decreased bone mineral density
Serious — stop and see a doctor
- Osteoporosis and fracture risk (long-term use)
- Thromboembolic events — DVT, pulmonary embolism (rare but serious)
- Cardiovascular events in high-risk patients
Important warnings
- ABSOLUTE CONTRAINDICATION: Do not use in pregnancy — highly teratogenic
- Premenopausal women must use effective contraception unless under fertility specialist care
- Bone density monitoring (DEXA scan) required with long-term use
- Do not use if allergic to letrozole or any ingredient
- Not for premenopausal breast cancer treatment (different from PCOS use — doctor will advise)
Conditions treated
Letrozole brands in Pakistan (1)
Click any brand to see full uses, dosage, side effects, prices, and warnings.
Frequently asked questions
What is Letrozole used for in Pakistan?
Letrozole is commonly used for Hormone receptor-positive (HR+) breast cancer (postmenopausal — adjuvant/extended adjuvant/metastatic), Ovulation induction in PCOS and infertility (off-label — gynaecologist supervised), Endometriosis-associated infertility (off-label). It belongs to the aromatase inhibitor drug class.
What is the typical dosage of Letrozole?
Typical adult dosing is described by manufacturers as: "As prescribed by oncologist or gynaecologist". Always confirm dose, duration, and timing with a qualified doctor or pharmacist — dose depends on indication, weight, age, kidney/liver function, and other medications.
What are the common side effects of Letrozole?
Common side effects include Hot flushes, Arthralgia — joint pain, Fatigue, Headache, Nausea, Bone loss / decreased bone mineral density. Most are mild and resolve as the body adjusts. Stop the medicine and contact a doctor if side effects are severe, persistent, or include allergic symptoms (rash, swelling, breathing difficulty).
When should I stop Letrozole and see a doctor?
Stop Letrozole and seek urgent medical care if you experience: Osteoporosis and fracture risk (long-term use); Thromboembolic events — DVT, pulmonary embolism (rare but serious); Cardiovascular events in high-risk patients. These are serious signs that need immediate attention.
Is Letrozole available without a prescription in Pakistan?
Prescription required.
What brands of Letrozole are available in Pakistan?
1 brand of Letrozole is listed on PakVita: 1 tablet. Browse the brand list below and click any name for prices, dosage, and full information.
Sources
- DRAP Registered Drug Products Database — Drug Regulatory Authority of Pakistan
- British National Formulary (BNF) — BMJ Group & Pharmaceutical Press
- WHO Model List of Essential Medicines, 23rd ed. — World Health Organization