Silodosin — brands & medicines in Pakistan
Pakistan mein Silodosin ke 1 brands available hain. Drug class: Selective Alpha-1A Adrenergic Receptor Antagonist (BPH / LUTS). Neeche se koi bhi brand select karein aur uses, dosage, side effects aur price dekhein.
Quick Answer
Silodosin is a selective alpha-1a adrenergic receptor antagonist (bph / luts) used in Pakistan for Benign Prostatic Hyperplasia (BPH) — urinary hesitancy, weak stream, frequent urination, Lower Urinary Tract Symptoms (LUTS) — nocturia, incomplete bladder emptying, Urgency-frequency syndrome due to BPH (frequent urination). Available as 1 brand. Prescription required. Always confirm dose with a doctor or pharmacist.
What is Silodosin?
Silodosin is a selective alpha-1a adrenergic receptor antagonist (bph / luts) used in Pakistan for a range of medical conditions. Doctors and pharmacists in Pakistan recognize Silodosin under multiple brand names — currently 1 listed on PakVita (1 capsule). The information below is a synthesis from DRAP-registered medicine entries, BNF, and WHO Essential Medicines references.
Common indications
- Benign Prostatic Hyperplasia (BPH) — urinary hesitancy, weak stream, frequent urination
- Lower Urinary Tract Symptoms (LUTS) — nocturia, incomplete bladder emptying
- Urgency-frequency syndrome due to BPH (frequent urination)
Indication and dose vary by medical condition, age, weight, and other factors. Always confirm with a qualified doctor or pharmacist before starting.
Typical dosage
As prescribed — 8mg once daily with a meal (food reduces peak levels, improves tolerability); start and monitor BP; dose reduce to 4mg OD in moderate renal impairment
This is a general adult guidance pattern based on the manufacturer's label for one of the Silodosin brands listed below. Children, elderly patients, pregnant women, and people with kidney or liver impairment usually need different dosing — confirm with your doctor.
Side effects
Common (usually mild)
- Retrograde ejaculation / absent ejaculation (VERY COMMON — ~28% — highly selective alpha-1A on seminal vesicle/vas deferens; reversible)
- Dizziness / orthostatic hypotension (less than tamsulosin/non-selective blockers)
- Nasal congestion / rhinitis
- Headache
- Diarrhoea
Serious — stop and see a doctor
- Intraoperative Floppy Iris Syndrome (IFIS) — cataract surgery complication — inform ophthalmologist
- Severe orthostatic hypotension — syncope / falls (elderly risk)
- Allergic reactions — angioedema, skin reactions
Important warnings
- EJACULATORY DYSFUNCTION (retrograde/absent ejaculation) — very common (~28%); REVERSIBLE on stopping; warn male patients BEFORE starting; significant QoL/fertility impact
- Intraoperative Floppy Iris Syndrome (IFIS) — inform ophthalmologist of alpha-blocker use BEFORE any cataract surgery
- Orthostatic hypotension — first-dose hypotension risk; consider starting at bedtime in elderly
- Syncope (first dose) — less than older non-selective alpha-blockers but still possible
- Not for patients with urinary retention (catheter-dependent) without urology review
- CONTRAINDICATED with strong CYP3A4 inhibitors (ketoconazole, ritonavir, clarithromycin)
Conditions treated
Silodosin brands in Pakistan (1)
Click any brand to see full uses, dosage, side effects, prices, and warnings.
Frequently asked questions
What is Silodosin used for in Pakistan?
Silodosin is commonly used for Benign Prostatic Hyperplasia (BPH) — urinary hesitancy, weak stream, frequent urination, Lower Urinary Tract Symptoms (LUTS) — nocturia, incomplete bladder emptying, Urgency-frequency syndrome due to BPH (frequent urination). It belongs to the selective alpha-1a adrenergic receptor antagonist (bph / luts) drug class.
What is the typical dosage of Silodosin?
Typical adult dosing is described by manufacturers as: "As prescribed — 8mg once daily with a meal (food reduces peak levels, improves tolerability); start and monitor BP; dose reduce to 4mg OD in moderate renal impairment". Always confirm dose, duration, and timing with a qualified doctor or pharmacist — dose depends on indication, weight, age, kidney/liver function, and other medications.
What are the common side effects of Silodosin?
Common side effects include Retrograde ejaculation / absent ejaculation (VERY COMMON — ~28% — highly selective alpha-1A on seminal vesicle/vas deferens; reversible), Dizziness / orthostatic hypotension (less than tamsulosin/non-selective blockers), Nasal congestion / rhinitis, Headache, Diarrhoea. Most are mild and resolve as the body adjusts. Stop the medicine and contact a doctor if side effects are severe, persistent, or include allergic symptoms (rash, swelling, breathing difficulty).
When should I stop Silodosin and see a doctor?
Stop Silodosin and seek urgent medical care if you experience: Intraoperative Floppy Iris Syndrome (IFIS) — cataract surgery complication — inform ophthalmologist; Severe orthostatic hypotension — syncope / falls (elderly risk); Allergic reactions — angioedema, skin reactions. These are serious signs that need immediate attention.
Is Silodosin available without a prescription in Pakistan?
Prescription required.
What brands of Silodosin are available in Pakistan?
1 brand of Silodosin is listed on PakVita: 1 capsule. Browse the brand list below and click any name for prices, dosage, and full information.
Sources
- DRAP Registered Drug Products Database — Drug Regulatory Authority of Pakistan
- British National Formulary (BNF) — BMJ Group & Pharmaceutical Press
- WHO Model List of Essential Medicines, 23rd ed. — World Health Organization