Sofosbuvir — brands & medicines in Pakistan
Pakistan mein Sofosbuvir ke 2 brands available hain. Drug class: Pan-genotypic Hepatitis C Antiviral. Neeche se koi bhi brand select karein aur uses, dosage, side effects aur price dekhein.
Quick Answer
Sofosbuvir is a pan-genotypic hepatitis c antiviral used in Pakistan for Chronic Hepatitis C infection — all genotypes (1–6), Cirrhotic patients (compensated and decompensated, with Ribavirin), Treatment-naive patients (first-time HCV treatment). Available as 2 brands. Prescription required. Always confirm dose with a doctor or pharmacist.
What is Sofosbuvir?
Sofosbuvir is a pan-genotypic hepatitis c antiviral used in Pakistan for a range of medical conditions. Doctors and pharmacists in Pakistan recognize Sofosbuvir under multiple brand names — currently 2 listed on PakVita (2 tablets). The information below is a synthesis from DRAP-registered medicine entries, BNF, and WHO Essential Medicines references.
Common indications
- Chronic Hepatitis C infection — all genotypes (1–6)
- Cirrhotic patients (compensated and decompensated, with Ribavirin)
- Treatment-naive patients (first-time HCV treatment)
- Treatment-experienced patients
- HCV-HIV co-infection
- Chronic Hepatitis C virus (HCV) infection — all genotypes
- HCV genotype 1 (with Ledipasvir combination)
- HCV genotype 2 (with Ribavirin combination)
Indication and dose vary by medical condition, age, weight, and other factors. Always confirm with a qualified doctor or pharmacist before starting.
Typical dosage
One tablet daily for 12 weeks (as prescribed by hepatologist)
This is a general adult guidance pattern based on the manufacturer's label for one of the Sofosbuvir brands listed below. Children, elderly patients, pregnant women, and people with kidney or liver impairment usually need different dosing — confirm with your doctor.
Side effects
Common (usually mild)
- Headache (sar dard)
- Fatigue (thakaan)
- Nausea (matlii)
- Nausea (matli)
- Insomnia
- Anaemia (especially with Ribavirin combination)
Serious — stop and see a doctor
- Severe bradycardia / dangerous decrease in heart rate
- HBV reactivation — worsening jaundice, dark urine, abdominal pain
- Signs of liver decompensation — extreme fatigue, confusion (hepatic encephalopathy), ascites
- Severe anaemia
Important warnings
- CONTRAINDICATED with amiodarone — risk of fatal bradycardia; never give to patients using amiodarone
- Risk of Hepatitis B (HBV) reactivation — HBV screening is essential before starting treatment
- In decompensated cirrhosis with Ribavirin: teratogenic — both men and women must use effective contraception for 6 months after completing Ribavirin
- Don't use Fosbu V Tablet if you are allergic to Sofosbuvir, Velpatasvir, or any ingredient
- Do not take with P-gp inducers such as Rifampicin or St. John's Wort — HCV treatment effectiveness may be reduced
- MUST be used as part of combination therapy — never as monotherapy
Sofosbuvir brands in Pakistan (2)
Click any brand to see full uses, dosage, side effects, prices, and warnings.
Frequently asked questions
What is Sofosbuvir used for in Pakistan?
Sofosbuvir is commonly used for Chronic Hepatitis C infection — all genotypes (1–6), Cirrhotic patients (compensated and decompensated, with Ribavirin), Treatment-naive patients (first-time HCV treatment), Treatment-experienced patients, and other indications. It belongs to the pan-genotypic hepatitis c antiviral drug class.
What is the typical dosage of Sofosbuvir?
Typical adult dosing is described by manufacturers as: "One tablet daily for 12 weeks (as prescribed by hepatologist)". Always confirm dose, duration, and timing with a qualified doctor or pharmacist — dose depends on indication, weight, age, kidney/liver function, and other medications.
What are the common side effects of Sofosbuvir?
Common side effects include Headache (sar dard), Fatigue (thakaan), Nausea (matlii), Nausea (matli), Insomnia, Anaemia (especially with Ribavirin combination). Most are mild and resolve as the body adjusts. Stop the medicine and contact a doctor if side effects are severe, persistent, or include allergic symptoms (rash, swelling, breathing difficulty).
When should I stop Sofosbuvir and see a doctor?
Stop Sofosbuvir and seek urgent medical care if you experience: Severe bradycardia / dangerous decrease in heart rate; HBV reactivation — worsening jaundice, dark urine, abdominal pain; Signs of liver decompensation — extreme fatigue, confusion (hepatic encephalopathy), ascites; Severe anaemia. These are serious signs that need immediate attention.
Is Sofosbuvir available without a prescription in Pakistan?
Prescription required.
What brands of Sofosbuvir are available in Pakistan?
2 brands of Sofosbuvir are listed on PakVita: 2 tablets. Browse the brand list below and click any name for prices, dosage, and full information.
Sources
- DRAP Registered Drug Products Database — Drug Regulatory Authority of Pakistan
- British National Formulary (BNF) — BMJ Group & Pharmaceutical Press
- WHO Model List of Essential Medicines, 23rd ed. — World Health Organization