Cilostazol Tablet Dosage Guide in Pakistan

Taking the correct dose and timing of Cilostazol is essential for treatment effectiveness. Absorption is considerably reduced when taken with food — so timing is important. This guide provides the adult dose, interaction-adjusted dose, and missed dose guidance.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-06-17

Dosage Guide

Quick Answer

The standard adult dose of Cilostazol is 100mg twice daily — 30 minutes before or 2 hours after food. If CYP3A4/2C19 inhibitor drugs (ketoconazole, omeprazole, erythromycin) are being taken concurrently, reduce the dose to 50mg twice daily. Avoid grapefruit juice. Do not use in heart failure.

Dose at a Glance

Adult Dose

100mg twice daily

Twice daily — morning and night

Max: 200mg/day (100mg twice daily) — reduce to 50mg BD with interacting drugs

Child Dose (Not applicable)

Not established — not recommended in children

N/A

Missed Dose

If a dose is missed, take it as soon as remembered. If the next dose is due soon (within 2 hours), skip the missed dose and continue on schedule. Never take a double dose.

Overdose

In case of overdose, contact a doctor or emergency room immediately. Cilostazol overdose can cause severe headache, rapid heartbeat, diarrhoea, and a drop in blood pressure.

Cilostazol Tablet Dosage (Kitni leni hai)

Taking the correct dose and timing of Cilostazol (Pletaal, Pletal) is essential for absorption. Always follow your doctor's prescription.

Adult Dose (Baalgon ke liye)

Standard Dose: 100mg twice daily Timing: 30 minutes BEFORE or 2 hours AFTER food Max Daily Dose: 200mg/day

Interaction-Adjusted Dose

Cilostazol levels increase with the drugs listed below — reduce the dose to 50mg twice daily:

CYP3A4 inhibitors: ketoconazole, erythromycin, diltiazem, fluconazole, itraconazole
CYP2C19 inhibitors: omeprazole, lansoprazole, esomeprazole

Child Dose (Bachon ke liye)

Cilostazol is not established in children — paediatric use is not recommended. Consult your doctor.

How to Take (Kaise leni hai)

Take 30 minutes before or 2 hours after food
Avoid grapefruit juice completely — it reduces absorption
Swallow with plain water
Maintain a routine — take at the same time every day

Best Time to Take (Kab leni chahiye)

Morning dose: 30 min before or 2 hours after breakfast
Night dose: 30 min before or 2 hours after dinner

With Food or Empty Stomach (Khali pait ya khane ke baad)

30 minutes BEFORE or 2 hours AFTER food — this timing is important. Bioavailability is considerably reduced when taken with food. Also avoid grapefruit juice.

Missed Dose (Dose chhoot jaye to kya karein)

Take as soon as remembered. If the next dose is due soon (within 2 hours), skip the missed dose — continue on schedule. Never take a double dose.

Overdose (Zyada Dose)

Cilostazol overdose can cause severe headache, rapid heartbeat, diarrhoea, and low blood pressure. Contact your doctor or emergency room immediately.

Dose Summary Table

Patient	Dose	Timing	Notes
Adult (standard)	100mg BD	30 min before / 2h after meal	Standard PAD dose
Adult (with interacting drugs)	50mg BD	Same timing	CYP3A4/2C19 inhibitors
Child	Not established	N/A	Avoid

The information in this guide is for educational purposes only. Always confirm the dose with your doctor or pharmacist.

Frequently Asked Questions

Cilostazol ki standard dose kya hai?

The standard adult dose is 100mg twice daily — 30 minutes before or 2 hours after food. If interacting drugs (ketoconazole, omeprazole, erythromycin, diltiazem) are being taken, use 50mg twice daily.

Cilostazol khane ke sath lein ya baghair?

Take 30 minutes before or 2 hours after food — taking it with food considerably reduces absorption. Also avoid grapefruit juice.

Kya cilostazol ki dose adjust hoti hai?

Yes — if CYP3A4 or CYP2C19 inhibitor drugs (such as ketoconazole, omeprazole, erythromycin, diltiazem) are being taken, use 50mg BD instead of 100mg BD. Confirm with your doctor or pharmacist.

Cilostazol kitni der mein kaam karna shuru karta hai?

Cilostazol's full effect comes in 4–12 weeks. Headache may be more frequent in the early weeks — this is normal and is controlled with paracetamol.

Agar dose bhool jaye to kya karein?

Take as soon as remembered. If the next dose is due soon (within 2 hours), skip — never double dose.

Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.