Diamicron Side Effects in Pakistan

A complete guide to the side effects of Diamicron. From common effects to serious warnings, including hypoglycemia, everything you need to know is on this page.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-07-02

Side Effects

Quick Answer

Common side effects of Diamicron include nausea and mild stomach upset. Serious effects such as hypoglycemia (low blood sugar) require immediate medical attention. Most patients tolerate Diamicron well at the correct dose. Contact your doctor if any side effect persists or worsens.

Side Effects at a Glance

Common

Nausea
Mild stomach upset
Headache

Serious — See a Doctor

Hypoglycemia (low blood sugar)
Severe allergic reaction (rash, swelling, difficulty breathing)
Liver function changes

When to See a Doctor Immediately

Signs of hypoglycemia (low blood sugar) — sweating, shaking, confusion, or fainting — that do not improve after taking a fast-acting sugar source
Severe allergic reaction — rash, swelling of the face or throat, or difficulty breathing
Persistent nausea, yellowing of the skin or eyes, or signs of liver problems

Diamicron Side Effects (Nuksanat)

Diamicron (Gliclazide) is generally safe when taken at the correct dose. However, like all medicines, it can cause side effects in some patients.

Common Side Effects (Aam Nuksanat)

Nausea
Mild stomach upset
Headache

These side effects are usually mild. If they continue, inform your doctor.

Serious Side Effects (Sanjeedah Nuksanat)

Hypoglycemia (low blood sugar) — see a doctor immediately
Severe allergic reaction (rash, swelling, difficulty breathing) — see a doctor immediately
Liver function changes — see a doctor immediately

Hypoglycemia Warning (Low Blood Sugar)

Hypoglycemia (low blood sugar) is a genuine and common risk with Diamicron and other sulfonylurea medicines. Watch for symptoms such as sweating, trembling, confusion, dizziness, and in severe cases unconsciousness. If these symptoms appear, treat immediately with a fast-acting sugar source (a sugary drink, glucose tablets, or juice), and seek emergency medical help if symptoms do not improve quickly. Skipping meals or drinking alcohol while taking Diamicron increases this risk.

When to See a Doctor (Kab Doctor Se Milna Zaroori Hai)

Signs of hypoglycemia that do not improve after taking a fast-acting sugar source
Severe allergic reaction — rash, swelling of the face or throat, or difficulty breathing
Persistent nausea, yellowing of the skin or eyes, or signs of liver problems

Warnings and Precautions (Ihtiyat)

Don't use Diamicron if you are allergic to Gliclazide or any ingredient
Avoid alcohol while taking Diamicron, as it can worsen the risk of hypoglycemia

Side Effects Summary Table

Type	Side Effect	Action
Common	Nausea	Monitor / inform doctor
Common	Mild stomach upset	Monitor / inform doctor
Common	Headache	Monitor / inform doctor
Serious	Hypoglycemia (low blood sugar)	Treat with fast-acting sugar, see a doctor immediately
Serious	Severe allergic reaction	See a doctor immediately

Reporting Side Effects

If you notice any unexpected side effect, report it on the DRAP pharmacovigilance portal: https://www.dra.gov.pk/pharmacovigilance

The information in this guide is for educational purposes only. If you notice any side effect, contact your doctor or pharmacist.

Frequently Asked Questions

What are the most common side effects of Diamicron?

The most commonly reported side effects of Diamicron include nausea and mild stomach upset. These are usually mild and go away on their own. Inform your doctor if they persist.

Can Diamicron cause low blood sugar?

Yes, hypoglycemia (low blood sugar) is a genuine and common risk with Diamicron and other sulfonylureas. Symptoms include sweating, trembling, confusion, and dizziness. Treat immediately with a fast-acting sugar source and seek medical help if symptoms persist.

Can Diamicron cause allergic reactions?

Yes, like all medicines, Diamicron can cause allergic reactions in some people. Signs include rash, itching, swelling, or difficulty breathing. Stop use and seek medical help immediately if this happens.

Is Diamicron safe to take for a long time?

Long-term safety depends on the condition and the patient. Your doctor will monitor for any signs of liver function changes if continued use is needed.

Does Diamicron affect the liver or kidneys?

Diamicron may require dose adjustment in patients with liver or kidney impairment. Your doctor will advise based on your test results and overall health condition.

Brand alternatives, same-class options, and other medicines used for the same conditions as Diamicron Tablet.

Brand alternatives

Other Gliclazide brands available in Pakistan.

All brands →

Gliclazide Tablet
Gliclazide
Servier / Local manufacturersRs. 130–265

Other diabetes medicines

Sibling medicines in the Diabetes Medicines class.

All in class →

Used for the same conditions

Other medicines commonly used for diabetes and overlapping conditions.

Diabetes hub →

Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.