Duphaston Tablet Side Effects in Pakistan

Duphaston Tablet side effects — a complete guide. From common effects to serious warnings — everything you need to know is on this page.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-04-24

Side Effects

Quick Answer

Common side effects of Duphaston Tablet include headache and nausea. Serious effects such as breathing issue require immediate medical attention. Most patients tolerate Duphaston Tablet well at the correct dose. Contact your doctor if any side effect persists or worsens.

Side Effects at a Glance

Common

Headache
Nausea
Breast pain or feeling tender

Serious — See a Doctor

Breathing issue
Fainting
Severe swelling

When to See a Doctor Immediately

Severe stomach pain
Persistent nausea or vomiting
Unusual vaginal bleeding

Duphaston Tablet Side Effects (Nuksanat)

Duphaston Tablet (Dydrogesterone) is generally safe when taken at the correct dose. However, like all medicines, it can cause side effects in some patients.

Common Side Effects (Aam Nuksanat)

Headache
Nausea
Breast pain or feeling tender

These side effects are usually mild. If they continue, inform your doctor.

Serious Side Effects (Sanjeedah Nuksanat)

Breathing issue — see a doctor immediately
Fainting — see a doctor immediately
Severe swelling — see a doctor immediately

When to See a Doctor (Kab Doctor Se Milna Zaroori Hai)

Severe stomach pain
Persistent nausea or vomiting
Unusual vaginal bleeding

Warnings and Precautions (Ihtiyat)

If you are allergic to dydrogesterone or any of the tablet's ingredients
If you have a history of liver disease

Side Effects Summary Table

Type	Side Effect	Action
Common	Headache	Monitor / inform doctor
Common	Nausea	Monitor / inform doctor
Common	Breast pain or feeling tender	Monitor / inform doctor
Serious	Breathing issue	See a doctor immediately
Serious	Fainting	See a doctor immediately

Reporting Side Effects

If you notice any unexpected side effect, report it on the DRAP pharmacovigilance portal: https://www.dra.gov.pk/pharmacovigilance

The information in this guide is for educational purposes only. If you notice any side effect, contact your doctor or pharmacist.

Frequently Asked Questions

What are the most common side effects of Duphaston Tablet?

The most commonly reported side effects of Duphaston Tablet include headache and nausea. These are usually mild and go away on their own. Inform your doctor if they persist.

Can Duphaston Tablet cause allergic reactions?

Yes, like all medicines, Duphaston Tablet can cause allergic reactions in some people. Signs include rash, itching, swelling, or difficulty breathing. Stop use and seek medical help immediately if this happens.

Is Duphaston Tablet safe to take for a long time?

Long-term safety depends on the condition and the patient. Your doctor will monitor for any signs of breathing issue if continued use is needed.

What should I do if I experience side effects from Duphaston Tablet?

For mild side effects, inform your pharmacist. For serious effects such as breathing issue, stop the medicine and contact your doctor immediately or go to the nearest hospital.

Does Duphaston Tablet affect the liver or kidneys?

Duphaston Tablet may require dose adjustment in patients with liver or kidney impairment. Your doctor will advise based on your test results and overall health condition.

Brand alternatives, same-class options, and other medicines used for the same conditions as Duphaston Tablet.

Other hormonal contraceptives & progestogens

Sibling medicines in the Hormonal Contraceptives & Progestogens class.

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Used for the same conditions

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Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.