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Entamizole DS Tablet: Uses, Dosage & Side Effects in Pakistan

Entamizole DS Tablet (Metronidazole 500mg + Diloxanide Furoate 250mg) ke quick uses, dose guide, side effects, warnings, aur buying price range.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated:

Prescription

Form

TABLET

Strength

500mg/250mg

Manufacturer

Abbott Laboratories (Pakistan) Ltd.

Estimated price

Rs. 30 - 50

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What is Entamizole DS Tablet used for?

  • Amoebic Dysentery
  • Giardiasis
  • Intestinal Parasitic Infections
Read full Uses guide →

How to take Entamizole DS Tablet?

Adult dose: 1 tablet three times daily (TDS) for 5–10 days

Child dose: Weight-based dose — consult your doctor

Read full Dosage guide →

Important warnings

  • Don't use Entamizole DS if you are allergic to Metronidazole or Diloxanide Furoate
  • NO ALCOHOL during treatment and 48 hours after — severe Disulfiram-like reaction
  • Avoid in first trimester of pregnancy

Entamizole DS Tablet Uses, Dosage, Side Effects & Price in Pakistan

1. Quick Info (Mukhtasir Maloomat)

FieldDetails
Brand NameEntamizole DS
Generic NameMetronidazole 500mg + Diloxanide Furoate 250mg
Strength500mg/250mg
FormTablet
Drug ClassAntiprotozoal / Antiparasitic Combination
ManufacturerAbbott Laboratories (Pakistan) Ltd.
PrescriptionRx — do not take without a doctor's advice
PriceRs. 30 – 50 approx (per tablet)
Packaging10 tablets blister pack

2. What is Entamizole DS? (Entamizole DS kya hai)

Entamizole DS is an antiprotozoal combination tablet by Abbott Pakistan. It contains Metronidazole (kills active trophozoite forms of amoeba and anaerobic bacteria) and Diloxanide Furoate (eliminates intestinal cyst forms). This dual action ensures complete eradication of amoebiasis — treating both the invasive and luminal stages of infection.

3. Uses (Fayde / Kis kaam aati hai)

  • Amoebic Dysentery
  • Giardiasis
  • Intestinal Parasitic Infections
  • Amoebic Liver Abscess

4. Who Should Take (Kis ko leni chahiye)

  • Adults with confirmed amoebiasis or giardiasis on stool test or clinical examination
  • Patients jinhe diarrhoea with blood/mucus ho (amoebic dysentery)
  • Patients with confirmed amoebic liver abscess (alongside IV therapy)

5. When NOT to Take (Kab nahi leni chahiye)

  • If you have an allergy to Metronidazole or Diloxanide
  • In the first 3 months of pregnancy (first trimester)
  • In active severe neurological disease
  • In people who drink alcohol — dangerous disulfiram reaction risk

6. Dosage (Kitni leni hai)

  • 1 tablet (500mg/250mg) three times daily (TDS)
  • 3 tablets per day for 5–10 days (infection type par depend)
  • 1.5g Metronidazole per day — do not exceed the recommended limit
  • Take it when you remember. If the next dose time is close, skip it. Never take a double dose.

7. How to Take (Kaise leni hai)

  • Three times daily — at equal intervals
  • Take with food — nausea and metallic taste are reduced
  • No alcohol at all during treatment and for 48 hours afterwards

8. Best Time (Kab leni chahiye)

  • Morning, afternoon, and night — take at equal spacing

9. Empty Stomach or After Food (Khali pait ya khane ke baad)

Taking Entamizole DS with food is recommended. Metallic taste and nausea are significantly reduced when taken with food.

10. Warnings (Ihtiyat)

  • Metronidazole + alcohol = severe Disulfiram-like reaction (nausea, vomiting, fast heartbeat, fainting)
  • Avoid in the first trimester. In the second/third trimester, only under strict doctor supervision.

11. Precautions (Ahm ehtiyaat)

  • Below 30°C, in a cool and dry place
  • Keep out of the reach of children

12. Side Effects (Nuksanat)

  • Metallic taste, Nausea (Matli), Headache (Sar dard), Dizziness, Dark urine
  • Peripheral neuropathy (numbness in hands/feet) — with prolonged use
  • Seizures (rare, high dose)
  • Severe allergic reaction — immediate emergency

13. Drug Interactions (Dawaon ke sath reaction)

  • Alcohol — severe Disulfiram-like reaction — avoid completely
  • Warfarin — bleeding risk may increase — monitor INR
  • Lithium — toxicity risk

14. When to See Doctor (Kab doctor ke paas jayein)

  • Numbness or tingling in hands or feet
  • Seizures or confusion
  • Symptoms do not improve within 3 days
  • Severe skin reaction or allergy signs

15. Alternatives (Sasti Dusri Dawaein)

Brand NameCompanySalt (Generic)
Flagyl TabletSanofi PakistanMetronidazole 400mg
Rozex TabletGetz/GSKMetronidazole 400mg
Dilox-M TabletVariousMetronidazole + Diloxanide

16. Price in Pakistan (Price kitni hai)

Pack SizePrice (Approx)
1 tabletRs. 30 – 50
10 tablets (1 strip)Rs. 300 – 500

17. FAQs (Aksar poochay jane walay sawalat)

Q: What is Entamizole DS used for?

A: It is used for amoebiasis, giardiasis, and intestinal parasitic infections.

Q: Can alcohol be consumed with it?

A: Absolutely not — a severe reaction occurs. Avoid alcohol for 48 hours after treatment too.

Q: What is the dose?

A: Three times daily — for 5 to 10 days. As per doctor's prescription.

Q: What is the price in Pakistan?

A: Rs. 30–50 per tablet. 10-strip Rs. 300–500.

Q: What are the side effects?

A: Metallic taste, nausea, dizziness. If hands or feet go numb, see a doctor.

18. Medical Review (Medical jaiza)

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-02-18

19. Disclaimer (Zaroori tanbeeh)

The information on this page is for awareness only. It is not medical advice. Always consult your doctor or pharmacist before taking any medicine. PakVita is not responsible for any harm.

Frequently Asked Questions

Entamizole DS kis kaam aati hai?

Doctors prescribe Entamizole DS for amoebiasis, giardiasis, and intestinal parasitic infections.

Kya Entamizole DS ke sath sharab pee sakte hain?

Absolutely not. Metronidazole + alcohol = severe reaction. Avoid alcohol completely during treatment and for 48 hours after.

Pakistan mein price kitni hai?

Entamizole DS tablet approximately Rs. 30–50 per tablet. 10-tablet strip Rs. 300–500 tak.

Kya Entamizole DS pregnancy mein safe hai?

Avoid in the first 3 months (first trimester). After that, take only on a doctor's advice.

Entamizole DS ke nuksanat kya hain?

Common side effects include metallic taste, nausea, and dizziness. If numbness in hands or feet or seizures occur, see a doctor immediately.

Sources

  1. DRAP Registered Products Database Drug Regulatory Authority of Pakistan
  2. WHO Model List of Essential Medicines, 23rd ed. (2023) World Health Organization
  3. British National Formulary (BNF) BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.