Entamizole DS Tablet Uses in Pakistan

Entamizole DS is the most commonly prescribed antiprotozoal combination in Pakistan for amoebiasis and parasitic infections.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-04-28

Uses

Quick Answer

Entamizole DS (Metronidazole 500mg + Diloxanide Furoate 250mg) is used to treat amoebic dysentery, giardiasis, and intestinal parasitic infections. Its dual-action formula eliminates both active amoeba and intestinal cysts, making it effective for complete eradication of amoebiasis.

Primary Uses at a Glance

Amoebic Dysentery (Amoebiasis)

Entamizole DS is the first-line treatment for intestinal amoebiasis caused by Entamoeba histolytica. Metronidazole kills the invasive trophozoites while Diloxanide clears the cysts, preventing relapse.

As prescribed by your doctor. Standard dose: 1 tablet TDS for 5–10 days.

Giardiasis

Entamizole DS (via Metronidazole component) is used to treat Giardia lamblia infections, which commonly cause watery diarrhoea, bloating, and malabsorption in Pakistan.

As prescribed by your doctor. Standard adult dose: 1 tablet TDS for 5 days.

Amoebic Liver Abscess

In combination with IV therapy, Entamizole DS is used as an oral component in the management of amoebic liver abscess under specialist supervision.

As prescribed by your specialist. Usually given alongside drainage or IV metronidazole.

Other Uses

Asymptomatic cyst passage (Diloxanide component clears luminal cysts)
Anaerobic bacterial infections (Metronidazole component)

Entamizole DS Tablet Uses (Fayde / Kis kaam aati hai)

Entamizole DS contains Metronidazole + Diloxanide Furoate and belongs to the antiprotozoal/antiparasitic combination group.

Primary Uses (Mukhya Istemal)

Amoebic Dysentery (Amoebiasis)
Giardiasis
Intestinal Parasitic Infections
Amoebic Liver Abscess (specialist supervision)

Who Should Take It (Kin logon ke liye)

Patients with confirmed Entamoeba histolytica or Giardia on stool test
Patients passing blood or mucus in stool (amoebic dysentery)

When NOT to Use (Kab nahi leni chahiye)

If allergic to Metronidazole or Diloxanide
During the first trimester of pregnancy
Those who consume alcohol

Summary

Entamizole DS is prescribed for amoebiasis and giardiasis. Always confirm with stool test before starting, and complete the full course.

The information in this guide is for educational purposes only.

Frequently Asked Questions

For which conditions is Entamizole DS most effective?

Entamizole DS is most effective for amoebic dysentery and giardiasis. The combination of Metronidazole and Diloxanide ensures both active parasites and dormant cysts are eliminated.

Can Entamizole DS be taken without a prescription?

Entamizole DS is a prescription (Rx) medicine. Do not self-medicate for loose motions — a stool test should confirm the infection type before starting treatment.

How long does Entamizole DS take to work?

Most patients notice improvement in diarrhoea and stomach cramps within 2–3 days. Complete the full 5–10 day course to ensure cysts are eliminated and prevent relapse.

Can Entamizole DS be taken long-term?

Entamizole DS is not for long-term use. It is prescribed for specific short courses of 5–10 days. Prolonged use of Metronidazole increases the risk of peripheral neuropathy.

What if symptoms don't improve after 3 days?

Consult your doctor. A repeat stool test may be needed to confirm the organism and its sensitivity. Do not increase the dose yourself.

Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.