Epival Tablet: Uses, Dosage & Side Effects in Pakistan

Epival Tablet Uses, Dosage, Side Effects & Price in Pakistan

1. Quick Info (Mukhtasir Maloomat)

2. What is Epival Tablet? (Epival kya hai)

Epival Tablet is manufactured by Abbott Laboratories (Pakistan) Ltd.. It contains Valproic Acid (as Sodium Valproate) and belongs to the Anticonvulsant / Mood Stabiliser class. It is prescribed in Pakistan for the conditions listed below. Always take it under medical supervision.

3. Uses (Fayde / Kis kaam aati hai)

• Epilepsy — generalised tonic-clonic seizures (Mirgi)
• Absence seizures in children
• Bipolar Disorder — acute mania and mood stabilisation
• Migraine prophylaxis
• Partial seizures

4. Who Should Take (Kis ko leni chahiye)

• Adults for whom a doctor has confirmed and prescribed this medicine
• Patients who do not have an allergy to this drug class
• With a doctor's prescription and guidance

5. When NOT to Take (Kab nahi leni chahiye)

• If you have an allergy to Valproic Acid or this drug class
• Without a doctor's prescription
• During pregnancy or lactation without medical advice

6. Dosage (Kitni leni hai)

• 600–1200mg/day in 2–3 divided doses (titrated by doctor)

• Initially 15–20mg/kg/day — titrated under paediatric neurologist

• Do not exceed the recommended limit

• Take it as soon as you remember. If the next dose is close, skip the missed dose. Never take a double dose.

7. How to Take (Kaise leni hai)

• As per your doctor's prescription
• Take at the same time every day
• With or without food

8. Best Time (Kab leni chahiye)

• As directed by your doctor
• Maintain a daily routine

9. Empty Stomach or After Food (Khali pait ya khane ke baad)

Confirm with your doctor or pharmacist. Generally, taking it with food reduces stomach irritation unless the packaging states otherwise.

10. Warnings (Ihtiyat)

• NEVER use in pregnancy — major teratogen (causes neural tube defects, developmental delay)
• Women of childbearing age must use effective contraception
• Do not stop suddenly — may trigger seizures (taper gradually)
• Monitor LFTs and full blood count periodically
• Risk of pancreatitis — report severe stomach pain

11. Precautions (Ahm ehtiyaat)

• Below 30°C, away from moisture.
• Keep out of the reach of children

12. Side Effects (Nuksanat)

• Weight gain (Wazan barh jaana)
• Tremor (Haath kaapna)
• Nausea/vomiting (Matli/Qay)
• Hair loss
• Drowsiness (Neend)

• Hepatotoxicity — liver failure (rare but fatal — especially in young children)
• Pancreatitis
• Valproate-induced encephalopathy
• Severe teratogenicity in pregnancy (foetal valproate syndrome)

13. Drug Interactions (Dawaon ke sath reaction)

• Carbamazepine — decreased valproate levels
• Lamotrigine — valproate increases lamotrigine levels (halve lamotrigine dose)
• Phenytoin — complex bidirectional interaction
• Aspirin — increases free valproate
• Carbapenem antibiotics — drastically reduce valproate levels

14. When to See Doctor (Kab doctor ke paas jayein)

• Severe allergic reaction — rash, breathing difficulty, swelling
• If side effects worsen or new symptoms develop
• If the infection or condition does not improve in 3–5 days

15. Alternatives (Sasti Dusri Dawaein)

16. Price in Pakistan (Price kitni hai)

(Note: Price depends on the pharmacy and pack size.)

17. FAQs (Aksar poochay jane walay sawalat)

Q: Epival Tablet kis kaam aata hai?

A: Epival (Valproic Acid) is prescribed by a neurologist or psychiatrist for epilepsy, bipolar disorder, and migraine prevention.

Q: Dose kitni hai?

A: 600–1200mg/day in 2–3 divided doses — the doctor adjusts the dose according to blood levels. Do not change the dose on your own.

Q: Pakistan mein price kitni hai?

A: Epival 250mg tablet approximately Rs. 12–20 per tablet.

Q: Kya Epival pregnancy mein safe hai?

A: Absolutely not — Valproate causes serious birth defects in pregnancy. Women of childbearing age must use effective contraception. Consult your doctor.

Q: Nuksanat kya hain?

A: Common: weight gain, hand tremor, nausea, hair loss. Serious: liver damage, pancreatitis.

18. Medical Review (Medical jaiza)

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-02-26

19. Disclaimer (Zaroori tanbeeh)

The information on this page is for awareness only. It is not medical advice. Always consult your doctor or pharmacist before taking any medicine. PakVita is not responsible for any harm.