Zestril Tablet: Uses, Dosage & Side Effects in Pakistan

Zestril Tablet Uses, Dosage, Side Effects & Price in Pakistan

1. Quick Info (Mukhtasir Maloomat)

2. What is Zestril Tablet? (Zestril Tablet kya hai)

Zestril Tablet contains Lisinopril — it is an ACE Inhibitor (Angiotensin-Converting Enzyme Inhibitor) class medicine. It dilates blood vessels, reducing the load on the heart and controlling blood pressure. In Pakistan it is manufactured by ICI Pakistan.

It is a DRAP-registered prescription medicine for hypertension (high blood pressure), heart failure, post-MI cardioprotection, and kidney protection in diabetes.

3. Uses (Fayde / Kis kaam aati hai)

• Hypertension
• Heart failure
• Post-MI cardioprotection
• Diabetic nephropathy

4. Who May Use It (Kis ko leni chahiye)

A healthcare professional should confirm that the indication, age and exact formulation match the patient’s needs. An ingredient match alone does not make another brand or formulation interchangeable.

5. When Not to Use (Kab nahi leni chahiye)

• PREGNANCY CONTRAINDICATED — absolutely forbidden in 2nd and 3rd trimester; risk of renal damage to the foetus and foetal death — stop immediately if pregnancy is detected
• Angioedema — if face, tongue or throat swells, go to emergency immediately; never take any other ACE inhibitor
• Hyperkalemia — use caution with potassium supplements or potassium-sparing diuretics
• First-dose hypotension — blood pressure may drop significantly when starting with diuretics; begin with a low dose

6. Dosage (Kitni leni hai)

Adult guidance

For adult hypertension, an initial dose is commonly 2.5–10 mg once daily and the usual maintenance dose is 20 mg once daily. Heart failure, kidney disease, diuretic use and low blood pressure require a different starting plan and monitoring.

Child guidance

A paediatric specialist must determine eligibility and a weight-based dose using age, blood pressure and kidney function. This page does not provide a home calculation.

Dose limits

Use the limit specified for your exact product and individual prescription. A strength printed on a pack is not automatically a recommended dose.

7. How to Use (Kaise leni hai)

Check the medicine name, strength and instructions before each course. Do not share a prescription or change its dose, duration or formulation without professional advice.

8. Timing (Kab leni chahiye)

Check the local leaflet or ask a pharmacist about food timing for this exact formulation; do not infer it from another medicine.

9. Missed Dose (Dose chhoot jaye)

Follow the exact leaflet or contact a pharmacist for missed-dose instructions. Do not double a dose or change a tapering or monitored treatment plan yourself.

10. Warnings (Ihtiyat)

• PREGNANCY CONTRAINDICATED — absolutely forbidden in 2nd and 3rd trimester; risk of renal damage to the foetus and foetal death — stop immediately if pregnancy is detected
• Angioedema — if face, tongue or throat swells, go to emergency immediately; never take any other ACE inhibitor
• Hyperkalemia — use caution with potassium supplements or potassium-sparing diuretics
• First-dose hypotension — blood pressure may drop significantly when starting with diuretics; begin with a low dose

11. Precautions (Ahm ehtiyaat)

Check allergies, pregnancy or breastfeeding, kidney and liver conditions, and all other medicines with the prescriber or pharmacist. Store according to the local pack and keep out of reach of children. Below 30°C, dry and cool place; keep out of the reach of children

12. Side Effects (Nuksanat)

Reported effects

• Dry persistent cough — in up to 20% of patients; if intolerable, discuss switching to an ARB (e.g. Losartan) with your doctor
• Dizziness (chakkar aana)
• Headache
• Fatigue (thakan)
• Hyperkalemia

Serious effects and warning symptoms

• Angioedema — swelling of tongue, throat or face
• Severe hypotension
• Acute kidney injury
• Fetal toxicity

These lists do not establish the frequency of an effect or prove that a new symptom is caused by this medicine. Persistent or worsening symptoms need assessment.

13. Interactions (Dawaon ke sath reaction)

NSAIDs can reduce the blood-pressure effect and increase kidney injury risk. Potassium supplements, potassium-sparing diuretics, salt substitutes containing potassium and lithium require monitoring. Do not combine with sacubitril/valsartan without the required prescriber-managed washout.

14. When to Get Help (Kab doctor se milein)

Seek emergency help for difficulty breathing, swelling of the face or throat, collapse, severe bleeding or suspected overdose. For the medicine-specific warning symptoms above, contact a clinician promptly. Bring the pack and a list of medicines.

15. Alternatives (Dusri dawaein)

Ask a pharmacist to compare the exact ingredients, strength, route and release type. A generic name alone does not prove dose equivalence. Do not substitute a combination product for a single-ingredient treatment.

16. Price in Pakistan (Price kitni hai)

A current price matched to the local strength and pack size has not been verified. Confirm the printed price, pack and expiry with a licensed pharmacy.

17. FAQs (Aksar poochay jane walay sawalat)

Q: Zestril Tablet kis kaam aati hai?

A: Zestril Tablet contains Lisinopril. Hypertension; Heart failure. The diagnosis and exact product determine suitability.

Q: Dose kaise confirm karein?

A: For adult hypertension, an initial dose is commonly 2.5–10 mg once daily and the usual maintenance dose is 20 mg once daily. Heart failure, kidney disease, diuretic use and low blood pressure require a different starting plan and monitoring.

Q: Bachon ke liye dose kya hai?

A: A paediatric specialist must determine eligibility and a weight-based dose using age, blood pressure and kidney function. This page does not provide a home calculation.

Q: Pakistan mein price kitni hai?

A: A current price matched to the local strength and pack size has not been verified. Confirm the printed price, pack and expiry with a licensed pharmacy.

Q: Nuksanat hon to kya karein?

A: Reported effects include Dry persistent cough — in up to 20% of patients; if intolerable, discuss switching to an ARB (e.g. Losartan) with your doctor; Dizziness (chakkar aana); Headache. Seek medical help for Angioedema — swelling of tongue, throat or face; Severe hypotension. A symptom list does not predict how often an effect occurs.

18. Editorial Information (Medical jaiza)

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-10-15

This correction adds ingredient-specific sources and separates verified facts from unverified local pack details. The recorded medical-review date is unchanged; this editorial correction is not a new clinician review. Foreign labels inform ingredient safety and do not establish Pakistani registration or every local pack’s instructions.

19. Disclaimer (Zaroori tanbeeh)

Educational information only. Confirm the diagnosis, local leaflet and individual prescription with a qualified clinician or pharmacist before starting, stopping or changing treatment.