Melatonin Tablet Side Effects in Pakistan

A complete guide to the side effects of Melatonin Tablet. From common effects to serious warnings — everything you need to know is on this page.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-07-09

Side Effects

Quick Answer

Common side effects of Melatonin Tablet include drowsiness, headache, and dizziness. Serious effects such as confusion in elderly patients or worsening depression require medical attention. Most patients tolerate Melatonin Tablet well at the correct dose. Contact your doctor if any side effect persists or worsens.

Side Effects at a Glance

Common

Drowsiness or daytime sleepiness
Headache
Dizziness

Serious — See a Doctor

Confusion or disorientation in elderly patients
Worsening of depression (rare)
Hormonal disturbances with prolonged use (rare)

When to See a Doctor Immediately

If drowsiness persists during the day and affects your ability to function
If you develop confusion, disorientation, or mood changes
If sleep problems do not improve after 2 weeks of use

Melatonin Tablet Side Effects (Nuksanat)

Melatonin Tablet (Melatonin) is generally safe when taken at the correct dose for short periods. However, like all supplements, it can cause side effects in some patients.

Common Side Effects (Aam Nuksanat)

Drowsiness or daytime sleepiness
Headache
Dizziness

These side effects are usually mild and dose-dependent. Using the lowest effective dose can help reduce them. If they continue, inform your doctor.

Serious Side Effects (Sanjeedah Nuksanat)

Confusion or disorientation in elderly patients — see a doctor immediately
Worsening of depression (rare) — see a doctor immediately
Hormonal disturbances with prolonged use (rare) — see a doctor immediately

When to See a Doctor (Kab Doctor Se Milna Zaroori Hai)

If drowsiness persists during the day and affects your ability to function or drive
If you develop confusion, disorientation, or mood changes
If sleep problems do not improve after 2 weeks of use

Warnings and Precautions (Ihtiyat)

Don't use Melatonin Tablet if you plan to drive or operate machinery after taking
Avoid combining with alcohol or other sedatives

Side Effects Summary Table

Type	Side Effect	Action
Common	Drowsiness / daytime sleepiness	Use lowest dose / avoid driving
Common	Headache	Monitor / inform doctor if persistent
Common	Dizziness	Monitor / inform doctor
Serious	Confusion in elderly patients	See a doctor immediately
Serious	Worsening depression	See a doctor immediately

Reporting Side Effects

If you notice any unexpected side effect, report it on the DRAP pharmacovigilance portal: https://www.dra.gov.pk/pharmacovigilance

The information in this guide is for educational purposes only. If you notice any side effect, contact your doctor or pharmacist.

Frequently Asked Questions

What are the most common side effects of Melatonin Tablet?

The most commonly reported side effects of Melatonin Tablet are drowsiness, headache, and dizziness. These are usually mild and dose-dependent. Taking the lowest effective dose helps minimise them. Inform your doctor if they persist.

Can Melatonin Tablet cause allergic reactions?

Yes, like all medicines, Melatonin Tablet can rarely cause allergic reactions. Signs include rash, itching, swelling, or difficulty breathing. Stop use and seek medical help immediately if this happens.

Is Melatonin Tablet safe to take for a long time?

Melatonin Tablet is intended for short-term use. Long-term safety data is limited. Your doctor will monitor for any hormonal effects if continued use is needed beyond a few weeks.

What should I do if I experience side effects from Melatonin Tablet?

For mild side effects such as daytime drowsiness, try reducing the dose. For serious effects such as confusion or mood changes, stop the supplement and contact your doctor immediately.

Does Melatonin Tablet affect the liver or kidneys?

Melatonin is processed by the liver. Patients with significant liver impairment may have higher melatonin blood levels. Your doctor will advise on appropriate dosing based on your health condition.

Brand alternatives, same-class options, and other medicines used for the same conditions as Melatonin Tablet.

Used for the same conditions

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Insomnia (Sleep Problems) hub →

Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.