Galvus Tablet (Vildagliptin) Uses in Pakistan

Galvus Tablet contains Vildagliptin — a DPP-4 Inhibitor (Gliptin class) manufactured by Novartis Pakistan. This guide covers all approved uses, who should take it, and when it should not be used.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-06-17

Uses

Quick Answer

Galvus Tablet (Vildagliptin) is used for Type 2 diabetes mellitus. It inhibits the DPP-4 enzyme to improve the body's natural insulin release — only when blood sugar is elevated (glucose-dependent). It can be taken alone (monotherapy) or in combination with Metformin. Always take as prescribed by your doctor.

Primary Uses at a Glance

Type 2 Diabetes Mellitus — Monotherapy

Galvus Tablet (Vildagliptin) is used in Type 2 diabetes patients to control blood glucose when diet and exercise alone are not sufficient. It blocks the DPP-4 enzyme to raise GLP-1 and GIP hormone levels, causing the pancreas to release insulin in a glucose-dependent manner.

As prescribed by your doctor. Standard adult dose: typically 50mg once or twice daily.

Type 2 Diabetes — Combination with Metformin

When Metformin (Glucophage) alone does not control blood sugar, doctors add Vildagliptin alongside Metformin. This combination provides a meaningful reduction in HbA1c and remains weight-neutral.

As prescribed by your doctor — the combination regimen is decided by your doctor.

HbA1c Reduction (Long-term Sugar Control)

Vildagliptin significantly reduces the 3-month average blood sugar level (HbA1c). Clinical trials have shown 0.5–1.0% HbA1c reduction on monotherapy and 1.0–1.5% on combination therapy.

As prescribed. Conduct regular HbA1c monitoring according to your doctor's plan.

Blood Sugar Control

Vildagliptin controls both fasting and post-meal blood sugar — especially reducing post-prandial glucose excursions.

Take regularly as prescribed — dosing is not dependent on meal timing.

Other Uses

Use in elderly diabetic patients
Overweight/obese Type 2 diabetes patients (weight-neutral action)

Galvus Tablet (Vildagliptin) Uses (Fayde / Kis kaam aati hai)

Galvus Tablet contains Vildagliptin — a DPP-4 Inhibitor used to control blood sugar in Type 2 diabetes.

Mechanism (Kaise Kaam Karta Hai)

Vildagliptin inhibits the DPP-4 (Dipeptidyl Peptidase-4) enzyme. This raises the level of GLP-1 and GIP hormones, which signal the pancreas to release insulin glucose-dependently — meaning only when blood sugar is elevated. This is why the risk of hypoglycaemia (low blood sugar) is lower when used alone.

Primary Uses (Mukhya Istemal)

Type 2 Diabetes Mellitus — alone (monotherapy) or in combination with Metformin
HbA1c reduction — improves the 3-month average blood sugar control
Post-meal blood sugar control — helps prevent blood sugar spikes after eating
Combination with Metformin — when Metformin alone is not sufficient

Who Should Take It (Kin logon ke liye)

Adults diagnosed with Type 2 diabetes
Patients who need better blood sugar control
If the doctor has specifically prescribed a DPP-4 inhibitor
Elderly patients

When NOT to Use Galvus Tablet (Kab nahi leni chahiye)

In Type 1 diabetes
In diabetic ketoacidosis (DKA)
In severe renal impairment without doctor's advice
With caution in liver disease — confirm with your doctor
During pregnancy or breastfeeding without medical guidance

Summary

Galvus Tablet (Vildagliptin) is prescribed for Type 2 diabetes management — alone or in combination with Metformin. Always take as prescribed by your doctor and do not change the dose yourself.

The information in this guide is for educational purposes only.

Frequently Asked Questions

Vildagliptin kis kaam aata hai?

Vildagliptin (Galvus) is used to control blood sugar in Type 2 diabetes. It inhibits the DPP-4 enzyme to improve natural insulin release — only when blood sugar is elevated. It can be given alone or in combination with Metformin.

Kya Galvus Type 1 diabetes mein bhi use hoti hai?

No. Galvus Tablet is only for Type 2 diabetes. It must not be used in Type 1 diabetes or diabetic ketoacidosis (DKA).

Kya Vildagliptin weight badhata hai?

No — Vildagliptin is weight-neutral. This is considered an advantage compared to sulfonylureas.

Vildagliptin aur Sitagliptin (Januvia) mein farq kya hai?

Both are DPP-4 inhibitors belonging to the same drug class. There is no major difference in efficacy. The choice depends on availability, price, and the doctor's preference — do not switch on your own.

Kitne arsa mein results nazar aate hain?

Blood sugar improvement can begin within the first week, but HbA1c improvement is fully measurable after 3 months. Conduct regular monitoring according to your doctor's plan.

Brand alternatives, same-class options, and other medicines used for the same conditions as Galvus Tablet (Vildagliptin).

Other diabetes medicines

Sibling medicines in the Diabetes Medicines class.

All in class →

Used for the same conditions

Other medicines commonly used for diabetes and overlapping conditions.

Diabetes hub →

Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.