Januvia Tablet Side Effects in Pakistan

A complete guide to the side effects of Januvia Tablet (Sitagliptin). From common effects to serious warnings — everything you need to know about this diabetes medicine is on this page.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-07-09

Side Effects

Quick Answer

Common side effects of Januvia Tablet include nasopharyngitis (cold-like symptoms) and headache. Serious effects such as acute pancreatitis and angioedema require immediate medical attention. Most patients tolerate Januvia Tablet well at the correct dose. Contact your doctor if any side effect persists or worsens.

Side Effects at a Glance

Common

Nasopharyngitis (common cold-like symptoms — runny nose, sore throat)
Headache
Upper respiratory tract infection

Serious — See a Doctor

Acute pancreatitis (inflammation of the pancreas)
Severe allergic reaction including angioedema (swelling of face, lips, throat)
Bullous pemphigoid (serious skin blistering condition)

When to See a Doctor Immediately

Severe or persistent abdominal pain — may indicate pancreatitis
Sudden swelling of the face, lips, tongue, or throat (angioedema) — emergency
Blistering or peeling of skin — may indicate bullous pemphigoid

Januvia Tablet Side Effects (Nuksanat)

Januvia Tablet (Sitagliptin Phosphate) is generally safe when taken at the correct dose under medical supervision. However, like all medicines, it can cause side effects in some patients.

Common Side Effects (Aam Nuksanat)

Nasopharyngitis (cold-like symptoms: runny nose, sore throat)
Headache
Upper respiratory tract infection

These side effects are usually mild. If they continue, inform your doctor.

Serious Side Effects (Sanjeedah Nuksanat)

Acute pancreatitis (severe abdominal pain) — see a doctor immediately
Severe allergic reaction including angioedema (face, lips, throat swelling) — emergency
Bullous pemphigoid (large fluid-filled skin blisters) — see a doctor immediately

When to See a Doctor (Kab Doctor Se Milna Zaroori Hai)

Severe or persistent abdominal pain — may indicate acute pancreatitis
Sudden swelling of the face, lips, tongue, or throat — angioedema is a medical emergency
Blistering or peeling of skin — may indicate bullous pemphigoid

Warnings and Precautions (Ihtiyat)

Do not use Januvia Tablet if you are allergic to sitagliptin or any ingredient
Not for use in type 1 diabetes or diabetic ketoacidosis
Monitor kidney function — dose adjustment required in kidney impairment

Side Effects Summary Table

Type	Side Effect	Action
Common	Nasopharyngitis (cold symptoms)	Monitor / inform doctor
Common	Headache	Monitor / inform doctor
Common	Upper respiratory infection	Monitor / inform doctor
Serious	Acute pancreatitis	See a doctor immediately
Serious	Angioedema	Emergency — seek help immediately

Reporting Side Effects

If you notice any unexpected side effect, report it on the DRAP pharmacovigilance portal: https://www.dra.gov.pk/pharmacovigilance

The information in this guide is for educational purposes only. If you notice any side effect, contact your doctor or pharmacist.

Frequently Asked Questions

What are the most common side effects of Januvia Tablet?

The most commonly reported side effects of Januvia Tablet include cold-like symptoms (nasopharyngitis) and headache. These are usually mild and go away on their own. Inform your doctor if they persist.

Can Januvia Tablet cause allergic reactions?

Yes, Januvia Tablet can cause severe allergic reactions including angioedema (sudden swelling of the face, lips, tongue, or throat). Stop use and seek emergency medical help immediately if this happens.

Is Januvia Tablet safe to take for a long time?

Long-term safety of Januvia Tablet depends on regular monitoring. Your doctor will monitor kidney function, blood glucose, and watch for any signs of pancreatitis or bullous pemphigoid during prolonged use.

What should I do if I experience side effects from Januvia Tablet?

For mild side effects, inform your pharmacist. For serious effects such as severe abdominal pain (pancreatitis) or skin blistering (bullous pemphigoid), stop the medicine and contact your doctor immediately.

Does Januvia Tablet affect the liver or kidneys?

Januvia Tablet requires dose adjustment in patients with moderate to severe kidney impairment. Kidney function should be checked before and during treatment. Your doctor will advise the appropriate strength based on kidney function results.

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Sources

DRAP Registered Products Database — Drug Regulatory Authority of Pakistan
WHO Model List of Essential Medicines, 23rd ed. (2023) — World Health Organization
British National Formulary (BNF) — BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.