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Saxagliptin Tablet: Uses, Dosage & Side Effects in Pakistan

Saxagliptin Tablet (Saxagliptin) ke quick uses, dose guide, side effects, warnings, aur buying price range.

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated:

Prescription

Form

TABLET

Strength

5mg (2.5mg for severe renal impairment)

Manufacturer

AstraZeneca Pakistan

Estimated price

Price not listed

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What is Saxagliptin Tablet used for?

  • Type 2 diabetes mellitus management
  • Blood glucose control as monotherapy or in combination therapy
  • Adjunct to diet and exercise for type 2 diabetes
Read full Uses guide →

How to take Saxagliptin Tablet?

Adult dose: 5mg once daily (2.5mg once daily in severe kidney impairment)

Child dose: Not recommended for patients under 18 years

Read full Dosage guide →

Important warnings

  • Don't use Saxagliptin Tablet if you are allergic to saxagliptin or any ingredient
  • Not for type 1 diabetes or diabetic ketoacidosis
  • Stop and seek medical help immediately if pancreatitis is suspected

Saxagliptin Tablet Uses, Dosage, Side Effects & Price in Pakistan

1. Quick Info (Mukhtasir Maloomat)

FieldDetails
Brand NameSaxagliptin Tablet (Onglyza — AstraZeneca brand)
Generic NameSaxagliptin
Strength5mg (2.5mg for severe renal impairment)
FormTablet
Drug ClassDPP-4 Inhibitor / Antidiabetic
ManufacturerAstraZeneca Pakistan
PrescriptionRx — do not take without a doctor's advice
PriceConfirm with your pharmacist
Packaging28–30 tablets per pack

2. What is Saxagliptin Tablet? (Saxagliptin Tablet kya hai)

Saxagliptin Tablet belongs to the class of drugs known as DPP-4 inhibitors, which are used primarily to manage type 2 diabetes. This medication works by blocking the enzyme dipeptidyl peptidase-4 (DPP-4) — a protein that breaks down hormones called incretins. By blocking DPP-4, saxagliptin helps the body maintain higher levels of GLP-1 and GIP, which are hormones that stimulate the pancreas to produce more insulin when blood sugar levels are high and reduce the amount of glucose produced by the liver. Patients with type 2 diabetes who need additional help controlling their blood sugar levels often take Saxagliptin Tablet.

Saxagliptin Tablet is part of a group of drugs that aim to manage blood sugar levels in individuals with type 2 diabetes. It works in conjunction with diet and exercise to provide better glucose control. While similar drugs in this class aim to achieve similar outcomes, Saxagliptin Tablet has its unique clinical profile and may be prescribed based on individual patient needs and tolerance. Always take Saxagliptin Tablet as directed by your doctor or pharmacist.

3. Uses (Fayde / Kis kaam aata hai)

  • Type 2 diabetes mellitus management
  • Blood glucose control as monotherapy or in combination therapy
  • Adjunct to diet and exercise for type 2 diabetes

4. Who Should Take (Kis ko lena chahiye)

  • Adults with type 2 diabetes who require additional blood sugar control beyond lifestyle measures
  • Patients where metformin alone is insufficient and a DPP-4 inhibitor is appropriate
  • Patients prescribed Saxagliptin by their endocrinologist or physician as part of a combination regimen

5. When NOT to Take (Kab nahi lena chahiye)

  • If you are allergic to saxagliptin or any ingredient
  • For type 1 diabetes or diabetic ketoacidosis
  • Not recommended under 18 years of age
  • If you have a history of serious hypersensitivity reactions to saxagliptin

6. Dosage (Kitni leni hai)

  • 5mg once daily as directed by your doctor
  • 5mg once daily; 2.5mg once daily in severe kidney impairment
  • Do not exceed 5mg per day without medical advice
  • If you miss a dose, take it as soon as you remember. If the next dose is close, skip the missed dose. Never take a double dose.

7. How to Take (Kaise lena hai)

  • Take once every day
  • At the same time each day to maintain consistent blood sugar control
  • Can be taken with or without food
  • Swallow the tablet whole with a glass of water; do not crush or split

8. Best Time (Kab lena chahiye)

  • Morning with or without breakfast is most common
  • Same time every day to maintain consistent blood glucose control

9. Empty Stomach or After Food (Khali pait ya khane ke baad)

Saxagliptin Tablet can be taken with or without food. The timing relative to meals is flexible, but consistency in daily timing is important.

10. Warnings (Ihtiyat)

  • Don't use Saxagliptin Tablet if you are allergic to saxagliptin or any ingredient
  • Do not use for type 1 diabetes or diabetic ketoacidosis
  • Stop immediately and seek emergency care if you develop signs of pancreatitis

11. Precautions (Ahm ehtiyaat)

  • Store in a cool, dry place below 30°C
  • Keep away from moisture and heat
  • Keep out of the reach of children

12. Side Effects (Nuksanat)

  • Upper respiratory tract infections (cold-like symptoms), headache, urinary tract infections
  • Pancreatitis (severe abdominal pain — stop immediately and see a doctor), severe hypoglycaemia when combined with insulin or sulphonylureas, heart failure exacerbation — see a doctor immediately

13. Drug Interactions (Dawaon ke sath reaction)

  • Potentiates hypoglycaemia (low blood sugar) when combined with insulin or sulphonylurea medicines
  • Strong CYP3A4 inhibitors (e.g. ketoconazole, clarithromycin) may increase saxagliptin blood levels — dose adjustment may be needed
  • Use with caution in patients with heart failure
  • Inform your doctor of all medicines you are taking, including herbal and OTC products

14. When to See Doctor (Kab doctor ke paas jayein)

  • If you develop sudden severe abdominal pain, especially radiating to the back (possible pancreatitis — a medical emergency)
  • If you experience swelling of legs or ankles, or difficulty breathing (possible heart failure)
  • If you experience very low blood sugar symptoms — confusion, trembling, sweating, rapid heartbeat

15. Alternatives (Sasti Dusri Dawaein)

Brand NameCompanySalt (Generic)
Januvia (Sitagliptin 100mg)MSD PakistanSitagliptin (DPP-4 Inhibitor)
Galvus (Vildagliptin 50mg)Novartis PakistanVildagliptin (DPP-4 Inhibitor)
Tradjenta (Linagliptin 5mg)Boehringer IngelheimLinagliptin (DPP-4 Inhibitor)

16. Price in Pakistan (Price kitni hai)

Pack SizePrice (Approx)
30 tablets (5mg)Confirm with pharmacist

(Note: Verified pricing for Saxagliptin Tablet in Pakistan was not available at time of publishing. A valid prescription is required. Please confirm the current price with a pharmacy.)

17. FAQs (Aksar poochay jane walay sawalat)

Q: Saxagliptin Tablet kis kaam aata hai?

A: Saxagliptin Tablet helps control blood sugar levels in adults with type 2 diabetes by blocking the DPP-4 enzyme. See the uses section on PakVita for full details.

Q: Saxagliptin kab lena chahiye?

A: Saxagliptin is taken once daily, with or without food, at the same time each day. Follow your doctor's prescription exactly.

Q: Pakistan mein Saxagliptin ki price kitni hai?

A: Specific verified pricing for Saxagliptin Tablet in Pakistan was not available at time of publishing. Please confirm the current price with your pharmacist.

Q: Saxagliptin pancreatitis kab cause karta hai?

A: Pancreatitis is a rare but serious risk. Seek emergency medical attention immediately if you develop sudden severe abdominal pain, especially pain that radiates to the back, while on Saxagliptin.

Q: Saxagliptin Tablet ke nuksanat kya hain?

A: Common side effects include upper respiratory infections and headache. Serious risks include pancreatitis and heart failure. Contact your doctor immediately if severe symptoms appear.

18. Medical Review (Medical jaiza)

Compiled by the PakVita Editorial Team · AI-assisted drafting with editorial review · Sourced from DRAP, WHO, BNF · Last updated: 2026-07-09

19. Disclaimer (Zaroori tanbeeh)

The information on this page is for awareness only. It is not medical advice. Always consult your doctor or pharmacist before taking any medicine. PakVita is not responsible for any harm.

Brand alternatives, same-class options, and other medicines used for the same conditions as Saxagliptin Tablet.

Frequently Asked Questions

Saxagliptin Tablet kis kaam aata hai?

Saxagliptin Tablet helps control blood sugar levels in adults with type 2 diabetes by blocking the DPP-4 enzyme. See the uses section on PakVita for full details.

Saxagliptin kab lena chahiye?

Saxagliptin is taken once daily, with or without food, at the same time each day. Follow your doctor's prescription exactly.

Pakistan mein Saxagliptin ki price kitni hai?

Specific verified pricing for Saxagliptin Tablet in Pakistan was not available at time of publishing. Please confirm the current price with your pharmacist.

Saxagliptin pancreatitis kab cause karta hai?

Pancreatitis is a rare but serious risk. Seek emergency medical attention immediately if you develop sudden severe abdominal pain, especially pain that radiates to the back, while on Saxagliptin.

Saxagliptin Tablet ke nuksanat kya hain?

Common side effects include upper respiratory infections and headache. Serious risks include pancreatitis and heart failure. Contact your doctor immediately if severe symptoms appear.

Sources

  1. DRAP Registered Products Database Drug Regulatory Authority of Pakistan
  2. WHO Model List of Essential Medicines, 23rd ed. (2023) World Health Organization
  3. British National Formulary (BNF) BMJ Group & Pharmaceutical Press

Medical disclaimer

This page is for educational use only and does not replace professional medical advice. Always confirm diagnosis, dose, and interactions with a qualified doctor or pharmacist before starting or changing any medicine.